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Impurities Chemicals

Our range of products include Afatinib Impurity J HCl, Calcipotriol EP Impurity D, 1 & 2-cyclobutanedimethanol Dib, Carboxy-2 & 5-tetramethylpyrrolidinyl-1-oxy, Boronic Acid Pinanediol Ester (3-Bromopropyl) and Corey Lactone Benzoate.

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Afatinib Impurity J HCl

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Features:
  • Afatinib Impurity J HCl
  • Catalog Number     CS-O-13084
  • CAS :1456696-14-2 (keto form)
  • Molecular Weight : 358.40
  • Molecular Formula : C18H23N4O4Cl
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)
Product Information :Impurity in commercial preparations of Afatinib.

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Features:
  • Calcipotriol EP Impurity D
  • Catalog Number     CS-O-31161
  • CAS :     112827-99-3
  • Molecular Weight :    412.60
  • Molecular Formula :    C27H40O3

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Features:
  • [(1S)-(1α,2β,3β)]-3-(2-Amino-6-iodo-7H-purin-7-yl)-1,2-cyclobutanedimethanol Dibenzoate Ester
  • Catalog Number : CS-O-13114
  • CAS : NA
  • Molecular Weight : 585.39
  • Molecular Formula : C25H24IN5O4
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :Impurity in commercial preparation of Lobucavir.

Synonyms :[(1S)-(1α,2β,3β)]-3-(2-Amino-6-iodo-7H-purin-7-yl)-1,2-cyclobutanedimethanol Dibenzoate Ester;((1S,2R,3S)-3-(2-amino-6-iodo-7H-purin-7-yl)cyclobutane-1,2-diyl)bis(methylene) dibenzoate

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Features:
  •  ( )-3-Carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy
  • Catalog Number : CS-T-10531
  • CAS : 50525-83-2
  • Molecular Weight : 186.23
  • Molecular Formula : C9H16NO3
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :The anionic form has been used to determine distribution coefficients of neutral solubilizates in anionic micelles.

Synonyms :R-( )rolidinyloxy

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Features:

  • ( )-(3-Bromopropyl)boronic Acid Pinanediol Ester
  • Catalog Number     CS-T-08826
  • CAS :    90084-37-0
  • Molecular Weight :    301.03
  • Molecular Formula :    C13H22BBrO2
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :A pinanediol boronic ester derivative used in the preparation of thrombin inhibitors.

Synonyms :(3aS,4S,6S,7aR)-2-(3-Bromopropyl)hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborole

References :Kettner, C. et al.: J. Biol. Chem., 265, 18289 (1990);

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Corey Lactone Benzoate

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Features:
  • (-)-Corey Lactone Benzoate
  • Catalog Number :    CS-T-13327
  • CAS :     39746-00-4
  • Molecular Weight : 276.28
  • Molecular Formula : C15H16O5
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

    Product Information :(-)-Corey Lactone Benzoate is a corey lactone derivative used in the preparation prostaglandin analogues for use as vasolidator as well as EP4 receptor agonists.

    Synonyms :(3aR,4S,5R,6aS)-5-(Benzoyloxy)hexahydro-4-(hydroxymethyl)-an-2-one

    References :Ohta, C. et al.: J. Org. Chem., 74, 8298 (2009); Skuballa, W. et al.: Angew. Chem., 93, 1080 (1981); Andersen, N.H. et al.: Prostaglandins, 22, 809 (1981);

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Features
  • (±) FTY720 Phosphate
  • Catalog Number :    CS-T-55109
  • CAS  :    402616-26-6
  • Molecular Weight :    387.45
  • Molecular Formula :    C19H34NO5P
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.

Synonyms :2-(S)-Amino-2-[2-( Mono(dihydrogen phosphate) Ester; (S)-FTY720-P;

References :Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005

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Features:
  • (3S)-3-Aminoazepane-1-carboxylic Acid tert-Butyl Ester
  • Catalog Number :    CS-T-01897
  • CAS :     625471-04-7
  • Molecular Weight :    214.3
  • Molecular Formula :    C11H22N2O2
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :(3S)-3-Aminoazepane-1-carboxylic Acid tert-Butyl Ester is used in the preparation of ureidothiophenes, as CHK1 kinase inhibitors for treating neoplasm.

Synonyms :(3S)-3-Aminohexahydro-1H-azepine Ester

References :Hardy, J., et al.: Science, 256, 184 (1992), Nguyen, J., et al.: Curr. Pharm. Des., 12, 4295 (2006), Scheff, S.W., et al.: Neurobiol. Aging, 27 1372 (2006),

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Features:
  • 1,2-Isonicotinyl Hydrazine
  • Catalog Number :    CS-P-00028
  • CAS :    NA
  • Molecular Weight :    242.24
  • Molecular Formula :    C12H10N4O2
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

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Features:

  • Catalog Number : CS-T-10531
  • CAS : 50525-83-2
  • Molecular Weight : 186.23
  • Molecular Formula : C9H16NO3
  • Shipping will be completely Free for all the purchases above USD 2000
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)
    Product Information :The anionic form has been used to determine distribution coefficients of neutral solubilizates in anionic micelles.

    Synonyms :R-( )rolidinyloxy


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Limonene Chemical

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Features:
  • ( /-)-Limonene
  • Catalog Number :    CS-O-11177
  • CAS :    138-86-3
  • Molecular Weight : 136.24
  • Molecular Formula : C10H16
  • Shipping will be completely Free for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :Impurity in commercial preparations of Limonene

Synonyms :Dipentene; ( /-)-p-Mentha-1,8-diene

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Canagliflozin Impurity I

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Features:
  • Canagliflozin impurity I
  • Catalog Number :    CS-O-10752
  • CAS :    NA
  • Molecular Weight :    562.73
  • Molecular Formula :    C36H28F2S2
  • Shipping will be completely Free for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :Impurity in commercial preparations of Canagliflozin.

Synonyms :5,5'-((4,4'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(methylene))bis(2-(4-fluorophenyl)thiophene);Canagliflozin Dimer.

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Features:
  •  Canagliflozin Open Ring Impurity
  • Catalog Number :    CS-O-10754
  • CAS :    NA
  • Molecular Weight :    462.53
  • Molecular Formula :    C24H27FO6S
  • Shipping will be completely Free for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :Impurity in commercial preparations of Canagliflozin.

Synonyms :1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol

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Features:
  • (-)-Dimethyl 2,3-O-isopropylidene-L-tartrate
  • Catalog Number  :  CS-T-2032
  • CAS  : 37031-29-1
  • Molecular Weight : 218.2
  • Molecular Formula : C9H14O6
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :(-)-Dimethyl 2,3-O-isopropylidene-L-tartrate is used as a reagent to synthesize ( )-Migrastatin, a natural macrolide compound produced by Streptomyces 1 & 2 that acts as a tumour migration cell inhibitor. (-)-Dimethyl 2,3-O-isopropylidene-L-tartrate is also a derivative of Tartaric acid (L-isomer

Synonyms :(4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5r

References :Chen, L., et al.: Nature, 464, 1062 (2010); Gaul, C., et al.: J. Am. Chem. Soc., 125, 6042 (2003); Heldin, E., et al.: Chromatographia, 32, 407 (1991)

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1-Boc-2-Cyanopiperidine

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Features:
  • (±)-1-boc-2-cyanopiperidine
  • Catalog Number :    CS-AD-00023
  • CAS :    940000-26-0
  • Molecular Weight :    210.2728
  • Molecular Formula :    C11H18N2O2
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

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Features:
  • (-)-(1S,2R)-1,2-Dihydro-1,2-naphthalenediol
  • Catalog Number :    CS-T-19065
  • CAS :     90365-29-0
  • Molecular Weight :    162.19
  • Molecular Formula :    C10H10O2
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)

Product Information :(-)-(1S,2R)-1,2-Dihydro-1,2-naphthalenediol is a derivative of Naphthalene, an abundant polycyclic aromatic hydrocarbon that is persistent, bioaccumulative, toxic and found in   smoke and urban air. ;Impurity in commercial preparations of Naphthalene

Synonyms :(iol

References :Bahuguna, A., et. al.: J. Pharm. Res., 5, 1600 (2012); Sutherland, K.M., et. al.: Am. J. Physiol., 302, L68 (2012);

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Features:
  • ( /-)-ortho-Cotinine Perchlorate
  • Catalog Number :    CS-T-13367
  • CAS  :    147732-32-9
  • Molecular Weight :    276.67
  • Molecular Formula : C10H13ClN2O5
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :Cotinine derivative.;Impurity in commercial preparations of Cotinine

Synonyms :1-Methyl-5-(2-pyridinyl)-2-pyrrolidinone Monoperchlorate

References :Sugasawa, S., et al.: Pharma. Bull., et al.: 2, 39 (1954), Thompson, J.A., et al.: J. Chromatog., 231, 53 (1982); Seeman, J.I., et al.: J. Org. Chem., 51, 1548 (1986)

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Canagliflozin R-Furanose

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Features:
  • Canagliflozin R-Furanose
  • Catalog Number:    CS-O-10769
  • CAS :    NA
  • Molecular Weight :    444.52
  • Molecular Formula :    C24H25FO5S
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :Impurity in commercial preparations of Canagliflozin.

Synonyms :(2R,3S,4R,5S)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)tetrahydrofuran-3,4-diol

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Canagliflozin-S-Furanose

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Features:
  • Canagliflozin-S-Furanose
  • Catalog Number :    CS-O-10751
  • CAS :     NA
  • Molecular Weight :    444.52
  • Molecular Formula :    C24H25FO5S
  • Shipping will be completely FREE for all the purchases above USD 2000.
  • Products for R&D use in accordance with 35 USC 271(e) A13(1)


Product Information :Impurity in commercial preparations of Canagliflozin.

Synonyms :(2R,3R,4R,5R)-2-((S)-1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)tetrahydrofuran-3,4-diol

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