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Andrographis Paniculata

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Andrographis Paniculata is a herbaceous plant native to India and Sri Lanka. It is widely cultivated in Southern Asia, where it is used to treat infections and some diseases often being used before  were created. Mostly the leaves and roots were used for medicinal purposes. Scientists have studied this herb for nearly thirty years. It is commonly known as Kalmegh. The Kalmegh of Ayurveda is an erect annual herb extremely bitter in taste in each and every part of the plant body. The plant is known in north-eastern India as Maha-Tita, meaning "King of Bitters". Since ancient times, Andrographis Paniculata is used as a wonderdrug in traditional Siddha and Ayurvedic systems of medicine as well as in tribal medicine in India and some other countries for multiple clinical applications. Andrographis Paniculata plant extract is known to possess a variety of pharmacological activities.

Andrographolide the major constituent of the extract is implicated towards its pharmacological activity.The herb is the well-known drug Kalmegh 'Green Chiretta' and forms the principal ingredient of a reputed household medicine ('alui'), used as a bitter tonic and febrifuge.The therapeutic value of Kalmegh is due to its mechanism of action which is perhaps by enzyme induction. The plant extract exhibits antityphoid and antifungal activities. Kalmegh is also reported to possess antihepatotoxic, antibiotic, antimalarial, antihepatitic, antithrombogenic, antiinflammatory, antisnakevenom, and antipyretic properties to mention a few, besides its general use as an immunostimulant agent. A recent study conducted at Bastyr University confirms anti-HIV activity of andrographolide.

Boswellia Serrata Extract

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Boswellia is a moderately sized tree which is known to have a lot of branches and is mostly available in the dry weather conditions. It can easily be found in the dry and hilly areas of the Indian sub continent. The tree trunk is known to be thick and it contains a gummy liquid which is essential in use for various purposes. It is more commonly known as a genus of trees which are recognized chiefly for their distinguished fragrant resin. These resins have many uses in the pharmacological areas more essentially as an anti-inflammatory and for treatment of arthritis.

The primary compounds thought to be responsible for the anti-inflammatory activity of Boswellia are known as Boswellic Acids. These compounds are thought to interfere with enzymes that contribute to inflammation and pain. The gum resin is used as an ointment for sores and has anti-inflammatory, antiatherosclerotic and antiarthritic activities. In some cases, Boswellia may be associated with mild gastrointestinal upset (heartburn, after-taste, and nausea), but there are no reports of serious adverse side effects. As Boswellia is used as an anti-inflammatory, it should probably be taken as needed to control pain and stiffness, rather than all the time as a maintenance herb. The typical recommended dose of boswellia is 450-1200mg per day of an extract standardized to contain approximately 30-65% boswellic acids. The extract should be consumed in 3 divide doses of 150-400mg each for approximately 2-3 months to achieve benefits in terms of reduced pain and improved mobility are noticed.

Garcinia Cambogia

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Garcinia Cambogia is a small fruit that resembles a miniature pumpkin. The fruit of Garcinia Cambogia has been traditionally used in food preparation and cooking, having a distinctive taste. Garcinia Cambogia has garnered a lot of attention of late as a popular natural weight loss aid. The reason is that the rind of this pumpkin like fruit is rich in a substance called hydroxycitric acid (HCA) which is popular in many natural weight loss products. The extract HCA, claimed to suppress appetite and enhance fat-burning. Specifically, hydroxycitric acid is a competitive inhibitor of adenosine triphosphate-citrate. In the cytosol, ATP citrate lyase catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (commonly referred to as acetyl CoA). Acetyl CoA is required for the synthesis of fatty acids, cholesterol and triglycerides.Oxaloacetate may enter the gluconeogenic pathway, which can lead to the production of glucose and glycogen.

Many researchers and experts assert that the putative antiobesity effect of hydroxycitric acid is due to suppression of fatty acid and fat synthesis. Additionally, hydroxycitric acid is believed to suppress food intake via an effect, which also supports the belief that HCA may assist in weight loss.In ancient Indian Ayurveda, it is said that the sour flavors, such as those from Garcinia Cambogia, activate digestion. Garcinia Cambogia has also been considered to make foods more filling and satisfying, and has been used routinely for many centuries with no known toxicity. This herb has been used historically in India to support the treatment of various health conditions.

Camellia Sinesis

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Green Tea is a true tea, meaning it is made solely with the leaves of Camellia Sinesis, that has undergone minimal oxidation during processing. The healthful properties of green tea are largely attributed to polyphenols, chemicals with potent antioxidant properties. In fact, the antioxidant effects of polyphenols appear to be greater than vitamin C. The polyphenols in green tea also give it a somewhat bitter flavor. Polyphenols contained in teas are classified as catechins. Green tea contains six primary catechin compounds: catechin, gallaogatechin, epicatechin, epigallocatechin, epicatechin gallate, and apigallocatechin gallate (also known as EGCG). EGCG is the most studied polyphenol component in green tea and the most active. Green tea also contains alkaloids including caffeine, theobromine, and theophylline. These alkaloids provide green tea's stimulant effects. Botanical evidence indicates that India and China were among the first countries to cultivate tea. Today, hundreds of millions of people drink tea around the world, and studies are now suggesting that green tea (Camellia Sinesis) in particular has many health benefits.

There are three main varieties of tea -- green, black, and oolong. The difference between the teas is in their processing. Green tea is made from unfermented leaves and reportedly contains the highest concentration of powerful antioxidants called polyphenols. Antioxidants are substances that scavenge free radicals -- damaging compounds in the body that alter cells, tamper with DNA (genetic material), and even cause cell death. Free radicals occur naturally in the body, but environmental toxins (including ultraviolet rays from the sun, radiation, smoke, and air pollution) also give rise to these damaging particles. Scientists believe that free radicals contribute to the aging process as well as the development of a number of health problems including cancer and heart disease. Antioxidants such as polyphenols in green tea can neutralize free radicals and may reduce or even help prevent some of the damage they cause.

Commiphora Mukul

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The Mukul myrrh (Commiphora Mukul) tree is a small, thorny plant distributed throughout India. Guggul and gum guggulu are the names given to a yellowish resin produced by the stem of the plant. This resin has been used historically and is also the source of modern extracts of Guggul.

Guggul contains resin, volatile oils, and gum. The extract isolates ketonic steroid compounds known as guggulsterones. These compounds have been shown to provide the cholesterol- and triglyceride-lowering actions noted for guggul. Guggul significantly lowers serum triglycerides and cholesterol as well as LDL and VLDL cholesterols (the "bad" cholesterols). At the same time, it raises levels of HDL cholesterol (the "good" cholesterol). As antioxidants, guggulsterones keep LDL cholesterol from oxidizing, an action which protects against atherosclerosis. Guggul has also been shown to reduce the stickiness of platelets-another effect that lowers the risk of coronary artery disease. One double-blind trial found guggul extract similar to the drug for lowering cholesterol levels. Other clinical trials in India (using 1,500 mg of extract per day) have confirmed guggul extracts improve lipid levels in humans.

Gymnema Sylvestre

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For centuries, Gymnema has been known as the destroyer of sugar and is traditionally used to aid in blood sugar and diabetes in India, and for the control of obesity in Japan. Gymnema supports the body's efforts to lose weight, helps the body for feel satisfied after eating less, curbs hunger, decreases carbohydrate and sugar cravings and lowers the ability to taste sweets. In the small intestine, the gymnemic acid in the herb discourages the absorption of excessive dietary sugar (including artificial sweeteners) into the blood stream, which helps support and balance blood sugar levels. The net effect is a lower desire for sweets while providing benefits to liver and pancreas functions. Long-term use of Gymnema can also help achieve a higher ratio of muscle mass to body fat due to increased insulin production.

Clinical trials have recorded benefits for the use of Gymnema in insulin and non-insulin dependent diabetic patients and hypoglycemics. These trials showed that Gymnema helped to lower and balance blood sugar, insulin, cholesterol, triglcerides, free fatty acids and serum amylase.

Melissa Officinalis

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Lemon Balm a member of the mint family, is considered a "calming" herb. It was used in the Middle Ages to reduce stress and anxiety, promote sleep, improve appetite, and ease pain and discomfort associated with digestion.Today, lemon balm is often combined with other calming, soothing herbs, such as valerian, chamomile, and hops, to enhance the overall relaxing effect.

Lemon balm, although native to Europe, is grown all over the world. It is grown not only in herb gardens but also in crops for medicine, cosmetics, and furniture polish manufacturing. The plant grows up to 2 feet in height.In the spring and summer, clusters of small, light yellow flowers grow where the leaves meet the stem. The leaves are very deeply wrinkled and range from dark green to yellowish green in color, depending on the soil and climate. If you rub your fingers on these leaves, your fingers will smell tart and sweet, like lemons. The leaves are similar in shape to mint leaves, and come from the same plant family. It is available as Lemon Balm Oil and Lemon Balm Extract Powder 5%, 10% & 20%.

Cassia Angustifloia

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senna leaves have been used for thousands of years as a potent cathartic and laxative remedy. Its name is derived from the arabic word "sena," and it has been used in ayurvedic and unani medicines since the ninth century. Senna plants grow along the nile in egypt and in southern and eastern india. The shrub grows to a height of approximately two feet, with green stems and pods and yellow, scoop-shaped leaves. Senna contains the dianthrone glycosides, sennosides a & b, which form during the drying process of the leaves and pods. The alternate leaves are even-pinnate, with four or five pairs of lanceolate or obovate leaflets that are brittle and greyish green in colour. The small yellow flowers are characterised by five spreading clawed petals. The fruit is in an oblong pod about 5cm long. The leaves and pods, or fruit, are used medicinally. People in northern africa and southwestern asia have used senna as a laxative for centuries. Senna was traditionally considered a "cleansing" herb because of its cathartic properties. More modern studies have found that senna is useful in treating constipation, whether it is caused by pharmaceuticals or natural means. In addition, the leaves were sometimes made into a paste and applied to various skin diseases. Ringworm and acne were both treated in this way.

the active substances in senna leaves are called sennosides. These molecules are converted by bacteria in the colon into another substance, rhein-anthrone, which has two beneficial effects, colon activity stimulation(which speeds bowel movements and improves digestion) and increased fluid secretion. The laxative effect of sennosides and their active metabolite, rhein anthrone, is due to inhibition of water and electrolyte absorption from the large intestine, which increases the volume and pressure of the intestinal contents. This will stimulate the colon motility resulting in propulsive contractions. In addition, stimulation of active chloride secretion increases water and electrolyte content of the intestine. These changes in active electrolyte transport are depend on calcium in the serosal surface. The laxative action of sennosides are partially via stimulation of colonic fluid and electrolyte secretion, and this secretion is mediated by stimulation of endogenous prostaglandin formation. Sennosides may be prepared as an enema or suppository or combined with a stool softener or bulk forming fiber laxative to form a combination laxative. Sennosides are strong purgative that should be taken with care and in proper dosage, especially for pregnant, menstruating, or postpartum women. It cannot be used where there is inflammation in the g. I. Tract because of irritation. The irritant effect upon the intestinal membrane may cause griping, pain or nausea, along with liquid stools or diarrhea for overdose.

Withania Somnifera

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Withania Somnifera plant is an evergreen perennial shrub which is usually found in the arid parts of India. It is commonly known by the names of Indian Ginseng & Winter Cherry. It sometimes grows as tall as seven feet and looks similar to a large potato plant. Although different parts of the plant have been used for medicinal purposes, the root is the primary source. The Latin name for the plant literally means "sweat of a horse" because the root smells like a damp horse.

Withania Somnifera is considered to be astringent, , , , antiviral and diuretic. It is often used internally for indigestion, heart disease, arthritis, back pain, and fevers. Ashwaganda has also been effective in relieving insomnia, convalescence, nervous exhaustion, and impotence. In the cases of mental health, Ashwaganda helps to prevent mental exhaustion in those who extend their energies more than they replenish, and also aids in recovery for those who have already exhausted themselves.


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Squalene is widely found in nature and sources include olives, palm oil and wheat germ oil. However, the largest concentration of Squalene is from deep sea Shark Liver Oil. Squalene is taken from sharks that are caught as a by product of fishing nets.

Processing and refining of Shark Liver Oil leads to three products:

a) Alkoxyglycerol rich Shark liver oil
b) Vitamin rich Shark liver oil
c) Squalene (99%) as an isolated material.

Squalene is a poly-unsaturated hydrocarbon liquid (C30 H50) which occurs naturally, ubiquitously in human tissue in small amounts. The non-saturated hydrocarbon C30H50, in order to stabilize, attaches hydrogen ions from water and acids in the body, and in the process, frees oxygen to the body. It was established that the non-mythical Squalene stimulates the metabolism of the body by supplying an abundance of oxygen to the tissues.

Several type of sharks live 3000 feet under the sea. At this depth, sunlight and oxygen are almost nil. The Atmospheric pressure is intense and conditions are harsh. The ability of these sharks to survive under a hostile environment is due largely to the size and content of their liver which contains pure Squalene. It is Squalene which supplies much of the volume of oxygen needed in their bodies, providing strength and stamina.

Squalene reduces various arthritic pain, helps body organs such as the kidneys, liver and gallbladder function properly, helps digestive system function properly by reducing gas troptosis conditions, helping to shrink hemorrhoids and curbing obesity. Squalene acts as a relaxant giving added vigor and vitality without the hyper-activity associated with other food supplements. Generates hair and smoothens skin, exhibits a penetrating action with immediate effects on topical applications, helps prevent various kinds of diseases and speeds up the healing process and boosts immune system.

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To,Cosqual Natural Extractors

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