Florocid is a parenteral preparation for the treatment of elephantoid changes in filariasis.
Mechanism of action of sodium fluoride in the treatment of elephantoid changes in filariasis is not well understood. However, Florocid therapy has been reported to provide effective clinical results in elephantoid changes due to filariasis with swellings upto three times the normal size and shape. In enormous swelling some subjective improvement has been noted. Florocidtherapy in some obstinate cases of chronic funiculitis with small hydrocele, recurrent filarial lymphangitis, filarial chronic pelvic cellulitis has been found to produce satisfactory clinical response. Softening of filarial swellings is also observed in a good number of cases with Florocid therapy, probably, due to some fibrolytic action of sodium fluoride. Improvement has also been noted in cases of chyluria.
Florocid is generally well-tolerated and no toxic symptoms are reported to occur with scheduled dosage. Some patients may complain of pain for a few days.
Dosage & Administration
Contents of one ampoule of sodium fluoride and one ampoule of procaine hydrochloride are to be drawn into a syringe and injected subcutaneously once a week for 4 weeks. The course may be repeated if necessary, after a rest period of 4 weeks. A preliminary anti-infective treatment facilitatesFlorocid therapy.
Ampoules of 4 x 1 ml of each in a carton.
Paxum Tablets & Injection
Paxum is a psychotherapeutic agent of the most popular and widely used benzodiazepine derivative, diazepam. In many individuals, it produces satisfactory anxiolytic effect in doses that do not cause clinically important sedation or impairment of psychomotor function. Other than its use as an anxiolytic agent, diazepam is also used as an anticonvulsant and a sedative and skeletal muscle relaxant. In addition to these therapeutic actions the drug lacks significant side effects outside of Central Nervous System and has low toxicityÑthe factors that have contributed to its wide-spread clinical use.
In elderly or debilitated patients and in children initial dosage should be small and increments made gradually. Patients on prolonged therapy should have periodic blood counts and liver function tests. Alcohol may alter the patients response to diazepam. Diazepam readily crosses the placenta and due care should be taken in using it in late pregnancy. I.V. administration should be done slowly to avoid the risk of apnoea. Withdrawal of the drug from patients receiving very high doses or for prolonged period of time should be gradual. The drug should not be mixed with i.v. fluids or solutions of other drugs. Safety and efficacy of parenteral diazepam has not been established in the neonates.
Concurrent use of PAXUM (Diazepam) with
alcohol, narcotic analgesics, sedative-hypnotics leads to increased detrimental effect on psychomotor skills, hypotension and muscular weakness.
With Cimetidine the effects of diazepam may be enhanced leading to development of side effects; with antacids (aluminium hydroxide) the absorption of diazepam may be delayed.
The clinical effects of benzodiazepines may be altered by cigarette smoking. Whether this interaction is due to induction of drug metabolizing enzymes or due to other effects in Central Nervous System is not well understood.
Keralin Skin Ointment
Cyclovarin is an effective non-hormonal, herbo-mineral formulation for the management of common functional gynaecological disorders.
Keralin formulation is based on various findings of effective clinical results with combination of salicylic acid and benzoic acid. Salicylic acid being actively keratolytic causes shedding of keratin layer of the epidermis facilitating the penetration of other medicaments into the skin and produces their action against the skin lesion. Salicylic acid has fungicidal property and has bacteriostatic action due to its property of interfering with the synthesis of pantothenic acid by bacteria. Benzoic acid, in combination with salicylic acid, is highly fungistatic and fungicidal and also has the advantage of exfoliating the upper layer of the skin in which the fungi are embedded. Benzoic acid has active germicidal property and its combination with salicylic acid help hyperemia to occur aiding in destruction of the parasite. Hydrocortisone acetate offers effective antiinflammatory and antiallergic properties with little side effects.
Allergic reactions may occur.
Keralin should be used with care over large areas of skin. There will be a warm feeling on the area where the ointment is applied.
Dosage & Administration
Rub a small quantity of Keralin on the affected parts of the skin. On tender parts of the body apply a smaller amount of the ointment carefully. There will be a warm feeling on the area where the ointment is applied.
Collapsible tubes 15 g.
Kafbin (Herbal Cough Syrup)
Kafbin is a herbal cough preparation with pronounced bronchocleansing action, for the effective management of respiratory diseases.
Kafbin, being an effective expectorant and having a pronounced bronchocleansing action, offers a rational approach in the treatment of chronic obstructive pulmonary diseases. As a very powerful mucolytic, Kafbinliquefies tenacious sputum and helps in expectoration. Kafbin is also a moderate but effective brochodilator. It relieves bronchospasms and thus reduces chances of asthmatic attacks-an important factor in the treatment of Copd. Kafbin also reduces inflammation of the upper as well as lower respiratory tracts and reduces congestion of the respiratory mucous membrane. Being a powerful pharyngeal demulcent, Kafbin glutionously and soothingly coats the pharynx and removes irritation.
Kafbin is useful in the treatment of chronic obstructive pulmonary diseases like chronic bronchitis, bronchial asthma, asthma with chronic bronchitis, bronchiectasis; cough due to pulmonary tuberculosis or caused by irritants; cough due to pharyngitis/laryngitis; pertusis.
Adults: 2 teaspoonfuls twice daily. In very severe conditions, the dosage may be increased to 2 teaspoonfuls thrice daily.
4 months to 1 year : 1/2 teaspoonful twice daily
1 year to 5 years : 1/2 to 1 teaspoonful twice daily
6 to 14 years : 1 to 1½ teaspoonfuls twice daily
or as directed by the physician.
Incase of productive cough, for still better results, it may preferably be taken with half a cup of luke warm water. For non-productive cough, it should be taken undiluted.
Phials 120 ml
Corto Quinol (Hydrocortisone Acetate And Clioquinol Cream)
Corto Quinol is a chemosteroid antibacterial, antifungal, antiallergic ointment for skin diseases
Acute and chronic dermatoses including atopic, allergicor contact dermatitis, impetiginized eczema, nummular eczema, infantileeczema, endogenous chronic infectious dermatitis,seborrhoeic dermatitis,chronic eczematoid, pyoderma, otitis externa, acne urticaria, lichensimplex chronicus, pruritus ani / vulvae, bacterial dermatoses,folliculitis and micotic infections like tinea (capitis,corporis, cruris,pedis), intertrigo, moniliasis.
Hypersensitivityto any of the ingredients, tuberculosis of the skin, ophthalmic use,viral skin infections including herpes simplex, vaccinia and varicella.
Thereare few reports of hypersensitivity or skin rash. On prolonged therapywith topical corticosteroids and particularly under occlusive dressingthere may be local adverse effects like itching, dryness, folliculitis,acne from eruptions, hypertrichiosis, hypopigmentation, allergic contactdermatitis, secondary infection.
In rare cases there may be irritation to sensitized skin. There are alsorare reports of staining of skin or discolouration of hair and nails.Use in pregnancy in large amounts or for prolonged periods or overextensive areas is not recommended. Prolonged use may cause overgrowthof non-susceptible organisms requiring appropriate therapy.
Dosage & Administration
Wash the affected parts with warm water. Do not apply any soap, detergents or antiseptics. Apply a thin layer of CORTO QUINOL 3 4 times daily.
Collapsible tubes 5 g
Iodonal Solution Ointment
Iodolan is a complex of iodine and the nonsurfactant polymer polyvinyl pyrrolidone, which releases free iodine slowly. Iodolan is a wide spectrum non-antibiotic, non-irritating, non-staining, microbicidal formulation
It is known that bactericidal activity persists since iodine is released gradually in this solution. As PVP-I is less irritating, Iodolan can be directly applied on the mucosa and wound surfaces. Even in the presence of blood, serum and necrotic tissue, PVP-I does not lose its bactericidal activity. Iodolan (PVP-I) is non-toxic and is free of the problems of induced bacterial resistance
Iodolan Solution is useful in topical management of herpes, moniliasis, degerming skin and treatment of wounds; preoperative preparation of skin, postoperative dressing.Iodolan Ointment is useful in topical treatment of boils, furunculosis, sycosis barbae, impetigo, paronychia, otitis externa, tinea infestations, cutaneous candidiasis, secondary infections in burns, wounds, ulcers.
Sensitivity to iodine.
Iodolan (PVP-I) presents iodine in a form of low toxicity. Hypersensitivity reaction and irritation may occur on application of Iodolan on skin & mucous membrane, albeit, severe reactions are rare.
In rare cases redness, irritation, swelling or pain persist or increase; if infection occurs use of Iodolan is to be discontinued. Keep Iodolan out of reach of children
Dosage & Administration
Iodolan Solution or Ointment is to be applied directly over the affected areas as is necessary; may be bandaged.
Phials 100 ml
Collapsible tubes 15 g
Tonoferon Drops (Pediatric)
TONOFERON SYRUP is a comprehensive preparation containing iron in colloidal form and essential haematopoietic factors-Vitamin B12 & Folic Acid along with Lysine for normal growth and its maintenance in children.
Both vitamin B12 and folic acid in TONOFERON DROPS, help cell metabolism, DNA synthesis and normal haemopoiesis. Deficiencies of both vitamin B12 and folic acid are common due to dietary inadequacies and particularly to infants born to mothers who are grossly deficient in folate or vitamin B12 during pregnancy. Supplementation of both folic acid and vitamin B12 is therefore necessary in such cases to prevent nutritional megaloblastic anaemia. Lysine provides dietary supplement, increasing appetite and weight gain in children
TONOFERON DROPS is useful for the treatment of common iron deficiency anaemia associated with dietary inadequacy in children. To provide dietary supplementation for rapid growth and weight gain in children and also for improving general metabolism and increasing appetite.
Patients with pernicious anaemia; hypersensitivity to any of the ingredients.
Mild gastric intolerance may occur in iron sensitive patients.
Underlying causes should be determined in cases where anaemia exists. Folic acid may mask the presence of pernicious anaemia due to reversal of blood picture to normal but not affecting the progression of neurological manifestations. In those with conditions tending to vitamin B12 depletion, serum B12 level should be regularly assessed during therapy and in children with vitamin B12 deficiency concomitant parenteral vitamin B12 therapy may be necessary
Concomitant therapy with antacids diminishes iron absorption. On concomitant administration of iron and tetracycline the absorption of both the drugs is markedly reduced leading to diminished therapeutic effectiveness
Infants less than one year : 5 drops twice daily.
Children above 1 year : 10 drops twice daily.
Phials 15 ml
Livotone (Bile Salts, Kalmegh, Cascara, Kurchi Liver Tonic)
Livotone liquid contains essential pharmacopoeial ingredients for all round care of common functional disorders of liver and gastrointestinal tract.
Vegetable bitters like Kalmegh and Kurchi stimulate appetite and increase the flow of digestive juice and help in the management of anorexia, flatulence, irregular bowels, etc. Kalmegh and Bile salts act as important cholagogues and choleretics. Cascara and Sodium phosphate help in satisfactory evacuation of the large gut. Bile salts and Sodium benzoate produce bacteriostatic action in the gut, prevent putrefaction and accelerate peristalsis
Livotone is useful in the management of viral, alcoholic or drug induced hepatitis; liver and gastrointestinal dysfunctions associated with poor appetite, indigestion, flatulence, griping, habitual constipation, fat intolerance; haemorrhoidal bleeding and allergic skin disorders; it is also useful as an adjuvant during growth period in children.
Complete biliary obstruction.
Overdose of Livotone may cause loose stools and gastrointestinal cramping which indicates for reduction in dosage.
Due caution should be employed for patients with gastritis, peptic ulcer and with symptoms of appendicitis.
Adults : 5-10 ml (1 to 2 teaspoonfuls approx.)
Children : 1-2 ml (1/4 to 1/2 teaspoonful approx.) twice daily before or after meals.
Phials 200 ml
Calron (Vitamin Mineral Tonic)
For optimum vitamin-mineral supplementation
CALRON provides supplementation of vitamins and minerals as desired in many special circumstances e.g. in elderly patients with chronic disease, for persons on low calorie diets, during pregnancy and lactation, in hypermetabolic conditions with pyrexial disease, with chronic usage of drugs like antitubercular, anticancer, contraceptives, etc. The supplementation of minerals like iron, calcium and vitamins are essential for maintaining certain body functions and gearing up the basic metabolic activities of the body, and in turn the individual becomes energetic active and develops a sense of well being.
CALRON is indicated for prophylactic nutritional supplementation in physiologically stressful conditions. These comprise (a) conditions causing reduced absorption or depletion of essential vitamins and minerals-inadequate intake due to reduced low calorie diets, anorexia or unbalanced diets; gastrointestinal disorders, chronic alcoholism, febrile illness, chronic diseases, chronic therapy with drugs like antibacterials, contraceptives, anticancer or other interfering agents, (b) conditions resulting in increased use of essential vitamins and minerals-recovery from surgery or trauma involving burns, fractures or other extensive tissue damages, pregnancy & menorrhagia.
Cyclovarin is usually without any side effects. Only, in some instances, there may be some abdominal discomfort, which can be overcome with any antacid.
10 ml twice daily after meals or, as directed by the physician.
Phials 300 ml, 400 ml
To,East India Pharmaceutical Works Limited