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Cortico Steroids

Widely beneficial for pharmaceutical industry, we offer a broad range of Corticosteroids. These products are formulated using quality ingredients, thus, maintaining accurate properties. With their excellent composition, these are beneficial in regulating the carbohydrates, proteins and fat content in the human body. With our industrial experience, we are able to offer the following products under this category:

Betamethasone

CAS No: 378-44-9
Molecular Formula: C22 H29 FO5
Molecular Weight: 392.46g/mole

We are a renowned processor, supplier and exporter of fine grade Betamethasone. It is a white or almost white crystalline powder having various specific characteristics. Insoluble in water sparingly dissolves in ethanol and methylene chloride. It should be stored in tight containers in the temperature ranging between 20°C to 300°C. We test it on specific measures thus checking its solubility, color and composition. Processed under proper conditions, it is free from impurities.

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Betamethasone Dipropionate

CAS No: 5593-20-4

Molecular Formula: C28 H37 FO7

Molecular Weight: 504.6 g/mole

Clients can avail from us Betamethasone Dipropionate, which is processed at our well-equipped manufacturing unit. It is a white to cream-white odorless powder, which is insoluble in water. Further in sparingly dissolves in alcohol and is freely soluble in acetone and chloroform. Preserved in tight containers, it should be stored at 250 excursions permitted between 150°C and 300°C. Our products are tested on varied parameters, so as to offer a flawless range.

Test	Specification
Characters	A white or almost white, crystalline powder.
Solubility	Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in alcohol.
Identification	Test B & C or test A, D, E & F
Identification A	The absorbance of the resulting solution at 419nm should not be more than 0.100 abs.
Identification B	The Infra red absorption spectrum should concordant with the spectrum obtained from std of Betamethasone Dipropionate or with the Reference Infra red spectrum graph.
Identification C	The principal spot in the chromatogram obtained with the test solution should be similar in position, colour in daylight, fluorescence in ultraviolet light at 365 nm and size to the principal spot in the chromatogram obtained with reference solution (a). The test should not valid unless the chromatogram obtained with reference solution (b) should show two clearly separated spots.
Identification D	The principal spot in each of the chromatograms obtained with the test solutions should be similar in position, colour in daylight, fluorescence in ultraviolet light at 365 nm and size to the principal spot in the chromatogram obtained with the corresponding reference solution. The principal spot in each of the chromatograms obtained with test solution (b) and reference solution (b) has an Rf value distinctly lower than that of the principal spots in each of the chromatograms obtained with test solution (a) and reference solution (a).
Identification E	The colour should be discharged and a clear solution should remain.
Identification F	The test solution should yellow and the blank should red.
Specific optical rotation	Between + 63.000 and + 70.000.
Related substances	Max. Individual impurity should not more than 1.50%.
	Any other individual impurity should not more than 1.00%.
	Total impurities should not more than 2.50%.
Loss on drying	Not more than 1.00%.w\w.
Assay	97.00 to 103.00%.w/w.
*In-house tests	(As per customer requirement).

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Betamethasone Valerate

CAS No: 2152-44-5

Molecular Formula: C27 H37 FO6

Molecular Weight: 476.59g/mole

Leveraging on our expertise, we offer our clients a range of Betamethasone Valerate. It is a white to practically white, odorless powder. With accurate composition it melts at about 190.00°C with decomposition. In order to restore its properties and avoid contamination, we store it in tight containers. Widely used as a necessary ingredient in varied medicines, our offered product has some specific features.

Test	Specification
Characters	A white or almost white,crystalline powder.
Solubility	Practically insoluble in water, freely soluble in acetone and in methylene chloride , soluble in ethanol (96 percent).
Identification	Test C & D OR tests A, B, E,F & G.
Identification A	It should comply with the test for specific optical rotation.
Identification B	The absorbance of the resulting solution at about 419nm should not more than 0.100Abs.
Identification C	The Infra red absorption spectrum should concordant with the spectrum obtained from std of Betamethasone Valerate or with the Reference Infra red spectrum graph.
Identification D	The principal spot in the chromatogram obtained with the test solution should be similar in position, colour in daylight, fluorescence in ultraviolet light at 365 nm and size to the principal spot in the chromatogram obtained with reference solution (a). The test should not valid unless the chromatogram obtained with reference solution (b) should show two clearly separated spots.
Identification E	The principal spot in each of the chromatograms obtained with test solution should be similar in position, colour in daylight, fluorescence in ultraviolet light at 365 nm and size to the principal spot in the chromatograms obtained with corresponding working std solution. The principal spot in each of the chromatograms obtained with test solution(b) and reference solution(b) has an Rf value distinctly lower than that of the principal spots in each of the chromatograms obtained with test solution(a) and working std solution (a).
Identification F	The colour should be discharged and a clear solution should remain.
Identification G	The test solution should be yellow and the blank should be red.
Specific optical rotation	Between + 75.000 and + 82.000.
Related substances	Max. Individual impurity should not more than 1.50%.
	Any other individual impurity should not more than 1.00%.
	Total impurities should not more than 3.00%.
Loss on drying	Not more than 0.50%
Assay	97.00 to 103.00%.w.r.t. dried substance.

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Betamethasone Sodium Phosphate

CAS No: 151-73-5

Molecular Formula: C22 H28 FNa2 O8 P

Molecular Weight: 516.40g/mole

Clients are offered with a finely processed range of Betamethasone Sodium Phosphate. This hygroscopic white, odorless powder is freely soluble in water and methanol. The pH value of our products ranges from 7.50 to 9.00. Processed under industrial guidelines, our product range possesses certain specific properties. Moreover timely delivered this quality range can be availed by our prestigious clients at market leading prices.

Test	Specification
Characters	A white or almost white powder; very hygroscopic.
Solubility	Freely soluble in water, slightly soluble in alcohol, practically insoluble in methylene chloride.
Identification	Test B & C OR tests A, C,D, E & F
Identification A	The absorbance of the resulting solution at about 450nm should not more than 0.100Abs.
Identification B	The Infra red absorption spectrum should concordant with the spectrum obtained from std of Betamethasone sodium phosphate or with the Reference Infra red spectrum graph.
Identification C	The principal spot in the chromatogram obtained with the test solution should be similar in position, colour in daylight, fluorescence in ultraviolet light at 365 nm and size to the principal spot in the chromatogram obtained with reference solution (a). The test should not valid unless the chromatogram obtained with reference solution (b) should show two spots which may however not be completely separated.
Identification D	The colour should be discharge and a clear solution should remain.
Identification E	The test solution should yellow and the blank should red.
Identification F	The solution should give reaction (a) of sodium and reaction (b) of phosphates.
Appearance of solution	Solution S should be clear and not more intensely coloured than reference solution B7.
pH	7.50 to 9.00.
Specific optical rotation	Between + 98.000 and + 104.000.
Related substances	Max. Individual impurity should not more than 2.00%.
	Any other individual impurity should not more than 1.00%.
	Total impurities should not more than 3.00%.
Inorganic phosphates	Not more than 1.00%
Water	Not more than 8.00%

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Clobetasol Propionate

CAS No: 25122-46-7

Molecular Formula: C25 H32 CIFO5

Molecular Weight: 466.97 g/mole

We bring forth for our clients a range of Clobetasol Propionate, availed by our clients at competitive prices. It is offered in crystalline powdered form in white to cream color. Practically insoluble in water, it slightly dissolves in benzene and diethyl ether. Further, we make sure to store them in tight and light-resistant containers. We have acquired a huge clientele in the market for our entire product range, owing to its increased usage.

Test	Specification
Characters	White or almost white, crystalline powder.
Solubility	Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 percent).
Identification	The Infra red absorption spectrum should be concordant with reference spectrum of Clobetasol propionate CRS.
Specific optical rotation	+112.00 to+118.00C on Dried basis.
Related substances	Impurity E: Not more than 0.70%
	Impurity D: Not More Than 0.50 %
	Impurity B,C: Not More Than 0.30 %
	Impurity A,L,M: Not More Than 0.20 %
	Unspecified impurity: Not More Than 0.10 %
	Total impurities: Not More Than 2.00%.
Loss on drying	Not more than 0.50%w/w
Sulphated Ash	Not more than 0.100%w/w
Assay	97.00 to 102.00%.w.r.t dried substance.

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Clobetasone Butyrate

CAS No: 25122-57-0

Molecular Formula: C26 H32 ClFO5

Molecular Weight: 479.00 g/mole

With the presence of our integrated manufacturing facility, we are able to offer an excellent array of Clobetasone Butyrate. Processed using fine grade ingredients, it acquires accurate composition and effective usage. Insoluble in water, our range is a white colored powder. Further, in order to check its efficiency, we conduct various tests of these products. Processed under specific conditions, these products have some unique properties.

Test	Specification
Characters	A white or almost white powder.
Solubility	Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in alcohol.
Identification A	The Infra red absorption spectrum should concordant with the spectrum obtained from working std of clobetasone butyrate with the Reference Infra red spectrum graph.
Identification B	The principal spot in the chromatogram obtained with the test solution be similar in position and size to the principal spot in the chromatogram obtained with reference solution (a).The test should not valid unless the chromatogram obtained with reference solution (b) should show two clearly separated spots.
Identification C	The color of the test solution should be yellow and that of the blank should be red.
Specific Optical Rotation	+ 127.000 to +133.000
Related Substance (By HPLC )	Any individual impurity: NMT 1.00%w/w. Other impurity: NMT 0.50%w/w. Total impurity : NMT 1.50%w/w
Loss on drying	Not more than 0.50%.
Assay	97.00 to 102.00%.

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Beclomethasone Dipropionate

CAS No: 5534-09-8

Molecular Formula: C28 H37 CIO7

Molecular Weight: 521.04 g/mole

We have acquired an eminent market position in offering our clients with a range of Beclomethasone Dipropionate. It is very slightly soluble in water, dissolves in chloroform and freely soluble in acetone and alcohol. Further, processed using quality ingredients it is very beneficial to be used in processing various medicines. We offer this range under the guidelines issued by the industry.

Test		Specification
Characters	:	White or almost white, crystalline powder.
Solubility	:	Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 per cent).
Identification	:	Test – A, B & C
Test – A	:	The Infra red absorption spectrum should be concordant with the spectrum obtained from std of Beclomethasone Dipropionate.
Test – B	:	The solution gives the reaction (a) of chlorides.
Test – C	:	Should complies with loss on drying test.
Specific rotation	:	Between + 108.00 and + 115.000.
Related substances	:
Impurity B,L	:	Not More Than 0.80%
Impurity M	:	Not More Than 0.50%
Impurity A, D	:	Not More Than 0.30%
Impurity C	:	Not More Than 0.10%
Unspecified Impurity	:	Not More Than 0.10%
Total impurities	:	Not More Than 1.50 %.
Loss on drying	:	Not more than 0.50%.
Assay	:	96.00 to 102.00% w.r.t. dried substance.
*In-house tests	:	(As per customer requirement)
*Particle size	:	90.00% < 10 micron, 99.00% < 50 micron.

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Dexamethasone Sodium Phosphate

CAS No: 2392-39-4

Molecular Formula: C22 H28 FNa2 O8 P

Molecular Weight: 516.41g/mole

Our firm holds a distinctive position in offering clients Dexamethasone Sodium Phosphate. It is a hygroscopic crystalline powder, having a slight odor of alcohol. Further, the pure quality is white or slightly yellow in color. Moreover, it is insoluble in chloroform and ether, very slightly soluble in dioxan and slightly soluble in alcohol. Our offered range is checked on various parameters before the final deliveries.

Test	Specification
Characters	A white or almost white powder; very hygroscopic. It shows polymorphism.
Solubility	Freely soluble in water, slightly soluble in alcohol, practically insoluble in methylene chloride.
Identification	Test B and C OR Tests A,C,D,E and F.
Identification A	The absorbance of the resulting solution at the maximum at about 419nm should not be less than 0.200 Abs.
Identification B	The Infra-red absorption spectrum should be concordant with the reference spectrum of Dexamethasone sodium phosphate CRS.
Identification C	The principal spot in the chromatogram obtained with the test solution should be similar, in position, colour in daylight, fluorescence in UV light at 365 nm and size to the principal spot in the chromatogram obtained with reference solution (a).The test should not valid unless the chromatogram obtained with reference solution (b) should show two spots which may, however, not be completely separated.
IIdentification D	The colour should fade and a clear solution should remain.
Identification E	The test solution should be yellow and the blank should be red.
Identification F	The solution should give the reaction (a) of sodium and reaction (b) of phosphate.
Appearance of solution	A 5% w/v solution in CO2 free water should be clear and not more intensely coloured than reference solution B7.
pH	7.50 to 9.50 pH.
Specific optical rotation	+75.000 to +83.000 on dried basis
Related substance (By HPLC )	Any individual impurity: NMT 0.50%. Any other impurity : NMT 1.00%
Inorganic phosphate	Not more than 1.00%w/w.
Ethanol	Not more Than 3.00%.
Ethanol and water	Not greater than 13.00%.
Assay	97.00% to 103.00%w/w on anhydrous basis & ethanol free substance.

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Mometasone Furoate

CAS No: 25122-46-7

Molecular Formula: C25 H32 CIFO5

Molecular Weight: 466.97 g/mole

We are a distinguished firm engrossed in manufacturing, supplying and exporting a range of Mometasone Furoat. A white crystalline powder, it is free from any sort of impurity. Having precise pH value and accurate compositions, this product is very effective in usage. The solubility and other characteristics of the products is checked by testing these on various parameters. With our team of experienced professionals, we are able to process a quality assured range of products.

Test		Specification
Characters	:	White or almost white, crystalline powder.
Solubility	:	Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 percent).
Identification	:	The Infra red absorption spectrum should be concordant with reference spectrum of Clobetasol propionate CRS.
Specific optical rotation	:	+112.00 to+118.00C on Dried basis.
Related substances	:	Impurity E: Not more than 0.70%
	:	Impurity D: Not More Than 0.50 %
	:	Impurity B,C: Not More Than 0.30 %
	:	Impurity A,L,M: Not More Than 0.20 %
	:	Unspecified impurity: Not More Than 0.10 %
	:	Total impurities: Not More Than 2.00%.
Loss on drying	:	Not more than 0.50%w/w
Sulphated Ash	:	Not more than 0.100%w/w
Assay	:	97.00 to 102.00%.w.r.t dried substance.

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Mr. Kirit Shah / Mr. Bipin Parikh
405 - 408, Navbharat Estate, 4th Floor, "B" Wing, Sewri (West)
Mumbai, Maharashtra - 400 015, India
Telephone: +(91)-(22)-24158860

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