About Us

We are engaged in manufacturing, marketing and out licensing patented Pharmaceuticals Formulations, NDDS, API’s (Active Pharmaceutical Ingredient) and chiral intermediates. Our range includes antineoplastic API, synthetic anticholinergic API, respiratory stimulant API, antirheumatic API, antidepressants, mydriatic API, API under development, synthetic anticholinergic drugs, antineoplastic ingredients, anticholinergic ingredients, antidepressant ingredients, API's under development and intermediates. These cater to the requirements of pharmaceutical industries and are accurately formulated to avoid any harm or side effects. Our range of products is specifically designed for oncology, antibiotics, pain and spasm management areas.

Our formulations are appreciated for following features:

• Accurate compositions
• Offered in the form of tablets, capsules and injections
• Effective formulations used for curing various ailments
• Packed in hygienic packing material
• Long shelf life
• No side effects

We have registered 150 products till date and are waiting for the registration of more than 700 formulations in future.

We have a state-of-the-art infrastructure facility with latest machinery and a well-equipped quality examination center. We have WHO-GMP approved dedicated facility for manufacturing of anticancer products (tablets, capsules, injections, liquids and lyophylised). With the help of latest technology, we also provide contract manufacturing for more than 10 companies. All the machines are operated by experienced technical staff to maintain high quality standard. Our company uses following machines in order to manufacture the entire range of products:

• Boilers
• Grinding machines
• Blenders
• Granulators
• Packing machines

Following international standards of manufacturing, we have been able to formulate anti cancer medicines in bulk. Here is the tabular representation of our production capacity:

We have a team of professionals who possess sound experience of the industry. Our professionals are employed only after we test them on the basis of their domain expertise, industrial experience and skills. In our team, we have professionals such as doctors, quality analysts, research associates, and sales & marketing personnel.

Our professionals work in close coordination with each other at different stages of production in order to ensure smooth and effective production of pharmaceuticals formulations, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral intermediates. The main objective of our professionals is to enhance the quality of our range of products and thereby maximize client satisfaction. Some of the basic functions of our professionals are as follows:

• Sourcing quality range of products
• Following proven methods of manufacturing
• Regular and stringent quality checking
• Continuous research for product enhancement
• Effective sales of our range of products

We have employed cross-hierarchical multi-functional network of experts from the organization as well from other institutions who continuously work towards developing new range of Pharmaceuticals Formulations, Antineoplastic Ingredients, Anticholinergic Ingredients, Antidepressant Ingredients, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral intermediates.

Quality has always been one of the prime motives in our company since inception. We manufacture our range of Pharmaceuticals Formulations, Antineoplastic Ingredients,  Anticholinergic Ingredients, Antidepressant Ingredients, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral intermediates that are at par with international standards. These are manufactured using state-of-the-art machines and latest methodology. In addition, our in-house quality inspection department strictly tests & monitors the entire range at every level of production. Owing to the quality we have more than 222 patents granted or pending using NDDS, nanotechnology, dendrimers and chiral chemistry. We test the entire range on following parameters:

• Compositions
• Effectiveness
• Shelf life
• Side effects

We are facilitated with a sophisticated research and development wing backed by a diligent team of R&D experts. All their endeavors are directed towards development of products that are in conformation with ISO standards. In order to provide quality range of products, we undertake extensive research activities so as to cater to the clients' requirements. This not only helps us to keep in line with the latest market trends and demands, but also enhances our market value. Owing to the dedicated efforts of our R&D experts major sales are from patented products from in-house R&D. The research conducted by them is based on the development of following parameters:

• Manufacturing process
• Technology

In addition, after complete assurance of the effectiveness and feasibility of the new development, our R&D team recommends it to the concerned department for further incorporation in the manufacturing process.

We conduct NDDS Research, which is focused over the formulations developed for colon delivery, brain delivery, osmotically engineered systems controlled delivery, biologically degradable polymers in controlled drug delivery and site specific drug delivery for enhanced efficacy and reduced toxicity. Owing to the latest R&D techniques, we are also working over development of novel drug delivery systems especially in the therapeutic areas like Antibiotics Cardiovascular, Respiratory, Oncology and NSAID’S .

Colon Targeted Drug Delivery

• Anti Cancer Drugs: 5-Flurouracil, Oxaliplatin Leucovorin
• Anti Inflammatory and Anti Spasmodic Drugs: Mesalazine, Corticosteroids, Camylofin
• Anti-Protozoal Drugs: Metronidazole, Tinidazole, Secnidazole

Brain Targeted Drug Delivery

• Neurological Drugs: CNS Drugs, Dopamine
• Site Specific Drug Delivery
• Anti-cancer Buccal Patches : Bleomycin
• Topical Formulations : Methotrexate Muco Adhesives

Osmotically Engineered Systems

Gastric Retention Systems

• Gastroprokinetic Drugs: Ondansetron
• Oral Delivery of Parentrals
• Vaccines, Peptides and other Parentrals Drugs

Modified Release Systems

Gastric Retention Systems:

• Gliclazide SR Tablets, Metformin and Gliclazide
• SR Tablets, Metoprolol SR Tablets

Multiple release systems:

• Cefixime OD Tablets, Cefixime +Cloxaciline+ Lactobacillus Tablets
• Matrix & Hydrogel Diffusion Systems:
• Ofloxacin OD Tablets, Metformin SR Tablets, Cefpodoxime Proxetil OD Tablets, Camylofin +Nimesulide OD Tablets, Paracetamol OD Tablet launched four speciality divisions operating in different therapeutic areas, to enable focus on maximum new product launches.

It was due to hard work of our R&D personnel that we developed Cefi XL (Number one in last 24 months as per IMS ORG) in July 2006, which was the No.1 new product launched in India. We have also developed multifunctional Chiral Pools of Carbohydrates, Monosaccharides, Amino Alcohols, Oxazolidinones etc. Currently, we are working on developing an economical dendrimer system for cosmetic applications and drug delivery and have filed several patents using dendrimers as a delivery platform.

We have carved out a distinct place in the business owing to our commitment to serve our clients with an unmatched range of Pharmaceuticals Formulations, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral intermediates. We have well developed distribution network spanning in many cities across the globe. It helps us to further improve the reach of our range in the market as well as making our products easily accessible to our client. Owing to the quality we have more than 222 patents granted or pending using NDDS, nanotechnology, dendrimers and chiral chemistry.

We have a wide marketing network comprising medical representatives and sales managers for meeting the requirements of 14000 Doctors (Gastroenterologists, General Surgeons, Gynecologists, Orthopedic Surgeons, Pediatricians, Physicians and Oncologists) and 56000 Pharmacies every month. We have also launched four speciality divisions to focus over development of new products. The products are developed for the catering to the requirements of Surgeons, Paediatricians, Diabetologists, Cardiologists Chest Physicians, Gynaecologists etc. We are currently supplying our range of products to 22 countries that include regulated markets of USA and Europe as well as non regulated markets of South East, Asia, Africa, Latin America, CIS.

Our clients are also based at Nigeria, Ethiopia, Kenya, Ghana, Zambia, Mozambique, Ivory Coast, Haiti, Dominican Republic, Trinidad & Tobago, Iraq, Georgia, Guatemala, Honduras, Myanmar, Thailand, Philippines, Hong Kong, Cambodia, Vietnam, Sri Lanka and Maldives. Further, we are planning to supply our range of products to Costa Rica, Ecuador, Chile, Venezuela, Bolivia, Uganda, Tanzania, Yemen, Oman, Jordan, Syria, Cameroon, Benin, South Africa, Pakistan, Bhutan, Indonesia and Malaysia.

We have been able to build a client base for ourselves in the international market with the help of our quality range of Pharmaceuticals Formulations, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral intermediates. We use state-of-the-art machinery and latest technology to process the entire range. Owing to the quality of our range we have been able to build a huge client base in India as well various parts of the world. Our range of products is in great demand because of following features:

• Quality range
• Safe to use
• Competitive prices
• Timely delivery
• Easy payment modes
• Safe packaging
• Wide distribution network

Further, we have manufacturing and licensing agreements with leading pharmaceutical companies, such as:

• An exclusive right given to NPIL to use our patents for camylofin injections, camylofin & paracetamol tablets and camylofin & paracetamol suspension / drops for the Indian market up to Nov 09
• Non exclusive rights of its patent of cefixime, cloxacilin with Lactobacillus and cefixime OD tablets given to NPIL

Manufacturing supply agreement for oncology formulations with:

• M/s. Unimark
• M/s. Zuventus
• M/s Emcure
• M/s Wockhardt
• M/s Cadila
• M/s Glenmark
• M/s Intas

We have also reached a licensing agreement with M/s. BDR Pharmaceuticals Int’l. Pvt. Ltd. for manufacturing Liposomal Doxorubicin.

Cefi XL

• License given to M/s. NPIL and Product Patent licensed non exclusively to M/s. NPIL
• Also licensed to M/s. Hetero and M/s. Wockhardt. Litigation still pending against M/s. Mankind, M/s. Macleod, M/s. Intas, M/s. FDC and M/s. Allembic

For framing successful business strategies and controlling our business operations effectively, we have appointed three directors. Our board of directors includes:

• Mr. R.V.S. Mani (Whole time Director)
• Mr. Sanjeev Khandelwal (Chairman & Managing Director)
• Mr. Vijay Goel

“We have a unique system whereby we question and review all the rules and keep redefining them as we go along.”

We as a society-responsible organization work with a holistic approach and understand the importance of all-round development of individual. For this reason, we have involved ourselves in the promotion of Arts, Sciences, Education, Sports and Music.

We work towards the development of:

The Arts (The mind)

• Development and promotion of Art/Cinema/Architecture through Osian’s Connoisseurs of Art Pvt. Ltd

Sports (The Body)

• Promotion and development of Squash, Football, Boxing and Yoga and Sportsmen through IOS India Pvt. Ltd.

• Promoting Music and Musicians through IOS India Pvt. Ltd

• Established 1800 Girls School and Inter College (Chameli Devi Khandelwal Kanya Vidyalaya in Mathura), UP
• Involved in Chetana’s Ramprasad Khandelwal Institute of Management, Mumbai
• Promoting further NLP and Radial Whole Brain thinking

Charity

Established Ramprasad Khandelwal Trust and Shreenath Khandelwal Trust for promoting Education and Health

In the recent years, we have given utmost attention to the research and development of Pharmaceutical Formulations, NDDS, & API’s (Active Pharmaceutical Ingredient) and Chiral Intermediates. We have licenses for:

Past 

Created Markets in India

• Oncology - Cyclophosphamide, Cisplatin, Bleomycin - Nippon Kayaku (Japan) / Asta Medica (Germany)
•  Pain and Spasm – Camylofin and Methocarbamol - Asta Medica /A.H. Robins (USA)
• Anaesthetic – Glycopyrrolate – A.H. Robins
• Respiratory Stimulants – Doxapram – A.H. Robins
• Iron Supplements – Iron Polymaltose – Hausmann Laboratories (Switzerland)
• Anti-tussive – Prenoxdiazine – Chinoin (Hungary)

Present 

Introduced Patented Products based on NDDS
(Marketed in India and out-Licensed for the Developing Countries)

• Camylofin combinations with Nimesulide/ Diclofenac – ANAFORTAN GROUP (Licensed to NPIL)
• Methocarbamol combinations with Diclofenac / Nimesulide.- ROBI GROUP  (Licensed to NPIL)
• Cefixime once a day - CEFI OD.(Licensed to NPIL) 
• Cefixime + Cloxacillin + Lactobacillus - CEFI XL. (Licensed to NPIL)

Future

Patents driven by NDDS, Nano and Dendrimers

(To be marketed in India and to be out Licensed to the developed countries)

• Silver Nano Gel for burns, wounds, acne etc
•  Gold Nano Gel for cosmetics
•  Dendrimers for cosmetics, antimicrobials etc
• Parenterals to oral delivery
•  Colon / Brain and site specific targeting