Family : Scrophulariaceae

Plant Parts used :  Total herb (dried).

Chemical constituents :  The main constituents of Bacopa Monnieri also known as Brahmi are Bacosides A & B (Saponin mixture).  The other constituents are Bacogenin A1 & A2,  Hersaponin, Monnierin and Brahmine.

Pharmacology : Alcoholic extract of the plant showed the considerable increase in learning performance in some clinical trials on rats and the activity is attributed to saponin mixtures containing primary bacosides. Recent study suggests that Bacopa Monnieri (Brahmi) may improve higher order cognitive process that are critically dependant on the input of information from our environment such as learning and memory.

Therapeutic uses: Improves intellect on consciousness and mental activity. Calms the mind and promotes relaxation – increases protein synthesis and activity in brain cells.  Improves memory, mental clarity and longevity.  Decreases anxiety, restlessness and senility. Commonly used to improve mental alertness and enhance learning and academic performance.

Standardisation : Bacopa monnieri dry extract is standardized to 20% and 40% Bacosides A & B.

Product Specifications

S.No	Parameters	Specification
1	Description	Brown Powder
2	Organoleptic tests Odour Taste	Characteristic Bitter
3	Identification	By TLC
4	Loss on Drying (at 105 0C)	NMT 6% w/w
5	Ash content	NMT 10% w/w
6	Solubility in water in alcohol	NLT 80% w/v NLT 70% w/v
7	Heavy Metals	NMT 20 PPM
8	Assay (on dried basis) Total Bacosides by HPLC	NLT 20% w/w
9	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella & E.Coli	Negative
	Coliforms

Family : Burseraceae

Plant Parts used :  Oleogum resin

Chemical constituents :  Boswellia Serrata also known as Salai Guggul contains 8 – 9% essential oil, 20 – 23% gum and about 50% resin. The gum resin of Boswellia serrata contains three triterpenic acids known as α, β,γ – Boswellic acids, ursan type compound with pentacyclic triterpens.

Pharmacology : Boswellia serrata gum resin has been reported to have analgesic, anti-inflammatory, anti-arthritic and anti-pyretic activity.  The other activities studied are anti-hyper lipidamic and anti-atheroselerotic and anti-cancer.

Therapeutic uses: The gum resin is used in rheumatic disorders and nervous diseases.  The oil obtained from the resin is used for skin disorders, anti-fungal activity. The extract of gum resin has been demonstrated to possess anti-bacterial and anti-inflammatory activity. It also found to exhibit sedative and analgesic effects.

Standardisation : Boswellia serrata dry extract is standardized to contain 65%, 70%, 75% and 80% Boswellic acids.

Product Specifications

S.No	Parameters	Specification
1	Description	Creamish yellow to Off white powder
2	Organoleptic tests Odour	Characteristic
3	Identification	By TLC
4	Loss on Drying (at 1050C)	NMT 5% w/w
5	Ash content	NMT  8% w/w
6	Solubility in water in alcohol	Insoluble  NLT 90%w/v
7	Heavy Metals	NMT 20 PPM
8	Assay (on dried basis) Total Boswellic acids By non aqueous Titration	NLT 65% w/w
9	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	SalmonellaÂ	Negative
	E.Coli	Negative

Product Specifications

Parameters	Specification
Description	Creamy yellow to Off white powder
Organoleptic tests Odour	Characteristic
Identification	Positive for Boswellic Acids by TLC
Loss on Drying (at 1050C)	NMT 5% w/w
Solubility in water in alcohol	In Soluble NLT 90% w/v
Heavy Metals	NMT 20 PPM
Assay (on dried basis) AKBBA by HPLC Total Boswellic acids By non aqueous Titration	NLT 30% w/w NLT 90% w/w
Microbiological Profile :
Total Plate Count	< 5000 cfu / g
Yeast & Moulds	< 100 cfu /g
Salmonella & Shigella	Negative
E.Coli	Negative

Family : Caesalpiniaceae

Plant Parts used :  Leaves & Pods

Chemical constituents :  The main constituents in Cassia Angustifolia, also known as Senna leaves & Pods are Sennosides A & B.  In addition, Sennosides C and D are also found in negligible amounts.  Free anthraquinones including aloe-emodin, chrysophanol and rhein with their glycosides are also present.

Pharmacology : The sennosides and other anthroquinone derivatives possess a laxative effect. Sennosides and their natural metabolites specifically influence large intestinal motility.  Acceleration of colonic transport seems to be a major component of the laxative action.  Anthraquinone works by irritating the lining of the upper intestines which provokes reflex muscular activity in the colon resulting in a bowel motion.

Therapeutic uses : Cassia Angustifolia or Senna is used as natural & time tested laxative in traditional as well as modern systems of medicine. Senna is a powerful cathartic used in the treatment of constipation, working through a stimulation of intestinal peristalsis.  In combination with Cinnamon, Ginger, Fennel etc., it can be used for easing nausea, biliousness, halitosis etc..

Standardisation : Senna extract is standardized to 10%, 15%, 20% and 60% Calcium sennosides.

Product Specifications

S.No	Parameters		Specification
1	Description		Pale brown coloured Powder
2	Organoleptic tests Odour		Characteristic
3	Identification		By TLC
4	Loss on Drying (at 105 0C)		NMT 5% w/w
5	Residue on Ignition (ROI)		NMT 16% w/w
6	Solubility in water in alcohol
7	Heavy Metals		NMT 20 PPM
8	Assay (on dried basis) Total Sennosides by UV- Spectro Photometer		NLT 20% w/w
9	Microbiological Profile :
	Total Plate Count		< 5000 cfu / g
	Yeast & Moulds		< 100 cfu /g
	Salmonella & E.Coli		Negative
	Coliforms		Negative

Family : Liliaceae

Plant parts used : Roots

Chemical constituents : Mainly saponin & herbal steroids (Stigmasterol & hecogenin).

Pharmacology: Chlorophytum Borivilianum (Safed Musli) has aphrodisiac, nourishing, strenghth promoting actions, antioxidant, general tonic and acts as strength enhancer.

Therapeutic uses : Aphrodisiac, tonic and pain reliever are used to cure general debility and impotency. Its power increases lactation in feeding mothers and lactating cows. It is being increasingly used in Ayurvedic and Pharmaceutical Industries.

Standardisation : Chlorophytum Borivilianum (Safed Musli) extract is standardized to 50% saponin content.

Product Specifications:

S.No	Parameters		Specification
1	Description		Free flowing powder
2	Color		Brown
3	Taste		Astringent
4	Loss on Drying (at 105 0C)		NMT 5% w/w
5	Solubility in water		NLT 75% w/w
6	Heavy Metals		NMT 20 PPM
7	Assay (on dried basis) Saponins by Gravimetry		NLT 50% w/w
8	Microbiological Profile :
	Total Plate Count		< 5000 cfu / g
	Yeast & Moulds		< 100 cfu /g
	Salmonella  & Shigella		Negative
	E.coli		Negative

Family : Labiatae

Plant Parts used : Dried roots.

Chemical constituents : Forskolin is the main active constituent of Coleus Forskolin (Coleus). Other minor constituents are de-acetyl forskolin, deoxy-forskolin and volatile oil.

Pharmacology : Forskolin – an active diterpenoid present in Coleus forskohlii root activates the enzyme adenylate cyclase which in turn initiates a myrid of critical events and processes within all the cells of the human body.  Adenylate cyclase and the chemicals activated by it are responsible for executing a various hormonal processes. Forskolin induced stimulation may lead to blood vessel dilation, inhibition of allergic reactions and possibly an increased secretion of thyroid harmone.

Therapeutic uses: Coleus Forskolin has been used in the treatment of congestive cardiomyopathy, glaucoma and bronchial asthma.  It is also used as anti-hypertensive, anti-thrombotic and broncho-spasmolytic.

Standardisation : Coleus forskohlii dry extract is standardized to 10%, 20% and 40% Forskolin by HPLC.

 Product Specifications

S.No	Parameters	Specification
1	Description	Reddish Brown Power
2	Organoleptic tests Odour	Characteristic
3	Identification	By TLC
4	Loss on Drying (at 105 0C)	NMT 5% w/w
5	Ash content	NMT 5.0% w/w
6	Solubility in water in alcohol	Insoluble NLT 90% W/V
7	Heavy Metals	NMT 20 PPM
8	Assay (on dried basis) Forskolin by HPLC	NLT 10% w/w
9	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella  & E.Coli	Negative
	Coliforms	Negative
	E.Coli	Negative

Family : Burseraceae

Plant Parts used :  Oleo-gum resin.

Chemical constituents : The oleo-gum resin contains a number of compounds- Guggulosterone-E, Guggulosterone-Z, Guggulosterone I – VI. Sesanin, camphorene and cambrane-A.

Pharmacology : The action of Commiphora Mukul (Guggul) has been investigated in two main areas i.e. 1)  Hypolipidaemic action 2)  Anti-inflammatory effect.  Oral administration of guggul produce lower cholesterol levels and lessening serum turbidity.

Therapeutic Uses: Commiphora Mukul also known as Guggul is useful to maintain cholesterol levels.  It reduces cholesterol, triglycerides and total lipid levels.  It also indicated in hyperlipidemia, rheumatic disorders, obesity and in ischaemic heart diseases.

Standardisation : Guggul extract contains 2.5% Guggulosterones by HPLC.

Product Specifications:

S.No	Parameters	Specification
1	Description	LightYellow - cream colouredPowder
2	Organoleptic tests Odour	Characteristic
3	Identification	By TLC
4	Loss on Drying (at 105 0C)	NMT 5% w/w
5	Solubility in water in alcohol	Partially soluble Partially soluble
6	Heavy Metals	NMT 20 PPM
7	Assay (on dried basis) Total Gugglesterones by (E+2)	NLT 2.5% w/w
8	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella  & E.Coli	Negative
	Coliforms	Negative

Family : Zingiberaceae

Plant Parts used :  Rhizome
.
Chemical constituents : The main active chemical complex compounds in Curcuma Longa or turmeric are curcuminoids, in which Curcumin is the main along with Demethoxycurcumin, Bis-Demethoxycurcumin, Dihydrocurcumin and oleoresin are also present

Pharmacology : Many studies on turmeric have revealed that the herb contains cholagogue-type substances which increase the secretion of bile. Principal among these substances is curcumin.  It also possess liver protective activity, detoxifying dangerous carcinogens, stimulating the gall bladder and activating as a free radical scavenger.  It lowers blood cholesterol and effects on weight loss.

Therapeutic uses: Curcuma Longa (Turmeric) possess anti inflammatory, antirheumatic, antiallergic, antibacterial, antioxidant and helps to prevent various cardio-vascular, viral and other chronic diseases. It is used in the form of lotion on external wounds and joints. It is also used as a colouring agent in food preparations.

Standardisation : Curcummin is purified to 95%

Product Specifications:

S.No	Parameters	Specification
1	Description	Orange-Yellow powder
2	Organoleptic tests Odour	Characteristic
3	Identification	By TLC
4	Loss on Drying (at 105 0C)	NMT 1% w/w
5	Ash content	NMT 0.5% w/w
6	Solubility in water in alcohol	Insoluble Soluble
7	Heavy Metals	NMT 20 PPM
8	Assay (on dried basis) Curcuminoids by UV	NLT 95% w/w
9	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella  & E.Coli	Negative
	Coliforms	Negative

Family : Euphorbiaceae

Plant parts used : Fruits

Chemical Constituents : Major chemicals present in Emblica Officinalis (Amla) are Tannins (gallic acid, elagic acid, phyllemblic acid and emblicol) and vitamin ‘C’ along with major qualities of alkaloids (Phyllantidine and phyllantine)

Pharmacology : Emblica Officinalis or Amla is an antioxidant with free radical scavenging properties due to the presence of high level  super oxide dismutage.  The tannins (Phylemblin ) isolated from the ethanolic extract of fruit pulp showed mild depressant action on CNS and also had a spasmolytic activity. The alcoholic extract has been found to have anti-viral properties. It has shown an increase in the cardiac glycogen and decrease in serum GOT, GPT and LDH suggesting a cardio protective action.  The extract nourishes and prevents ageing.

Therapeutic use : Anti oxidant, Antacid.  It is one of the ingredients in Triphala and useful in dyspepsia, constipation, piles, enlarged liver and spleen.  It is also useful in cardiac diseases.  It is considered as one of the foremost rejuvenative drugs imparting a long healthy life and weight gain.

Standardisation :  Emblica officinalis dry extract is standardized to 30% Tannins.

Product Specifications:

S.No	Parameters	Specification
1	Description	Light Brown Powder
2	Organoleptic tests Odour	Astringent & Sour
3	Identification - Test for Tannins by Ferric chloride solution	Positive
4	Loss on Drying (at 105 0C)	NMT 6% w/w
5	Ash content	NMT 8% w/w
6	Solubility in water in alcohol	Insoluble Soluble
7	Heavy Metals	NMT 20 PPM
8	Assay (on dried basis) Tannins by Titrimetry	NLT 30% w/w
9	Microbiological Profile :
	Total Plate Count	< 5000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella  & E.Coli	Negative
	Coliforms	Negative

Product Specifications:

Parameters	Specification
Description	Off white to Cream colored powder
Organoleptic tests Odour taste	Astringent Sour
Identification-Test for Tannins by Ferric chloride solution	Positive
Loss on Drying (at 105 0C)	NMT 6% w/w
Ash content	NMT 10% w/w
Solubility in water in alcohol	NLT 80% w/v NLT 70% w/v
Heavy Metals	NMT 20 PPM
Assay (on dried basis)Tannins by Titrimetry Vitamic C (as per IP method)	NLT 20% w/w NLT 20% w/w
Microbiological Profile :
9.1Total Plate Count	< 5000 cfu / g
9.2 Yeast & Moulds	< 100 cfu /g
9.3 Salmonella &E.Coli	Negative
9.4 Coliforms	Negative

Family: Guttiferae

Plant parts used : Dried fruit rind.

Chemical Constituents : The chemical constituents present in Garcinia Cambogia (Malabar Tamarind) are:

• ( - ) Hydroxy citric Acid
• ( - ) Hydroxy citric acid lactone
• Garcinol
• Isogarcinol
• Cyanidin -3- sambubioside

Pharmacology : Extensive studies on animals shows that Hydroxy Citric Acid present in Garcinia cambogia suppresses the fatty acid synthesis, lypogenesis, food intake and induced weight loss.  Invitro studies revealed inhibitions of fatty acid synthesis and lypogenesis from various precursors. The success of  ( - ) hydroxycitric acid in promoting loss of body fat is linked to its relationship with lyase.

Therapeutic uses : It is extensively used in weight management, haemorrhoids, diarrhoea, dysentery and flatulent colic.

Standardisation :  Garcinia cambogia dry extract is standardized to 50% & 60% HCA ( Calcium salt and    50%, 60% & 65% HCA – Calcium potassium salt – Water soluble).

Product Specifications:

S.No	Parameters	Specification
1	Description	Off white Buff colored powder
2	Organoleptic tests Odour Taste	Odourless Salty taste
3	Identification for HCA & Calcium	Positive
4	Loss on Drying (at 105 0C)	NMT 5% w/w
5	Solubility in water in 50% v/v alcohol	Sparingly soluble Insoluble
6	Heavy Metals	NMT 20 PPM
7	Assay (on dried basis) (-HCA) content by HPLC Calcium content	NLT 50% w/w 14 ± 2 % w/w
8	Microbiological Profile :
	Total Plate Count	< 1000 cfu / g
	Yeast & Moulds	< 100 cfu /g
	Salmonella &E.Coli	Negative
	Coliforms	Negative

Family : Leguminosae

Plant parts used : Seeds

Chemical constituents : Glycine Max, Soya bean contains various important constituents, some of the pharamacologically active ones are Isoflavones, Saponins & lipids groups.

Pharmacology: Literature available reveals that the Soya Isoflavones acts in four distinct ways,

• As a estrogen & anti-estrogens
• As cancer enzyme inhibitor
• As antioxidant &
• As immune enhancer.

The clinical trials conducted by scientist, suggest that the isoflavones may confer health benefits related to Cancer, Cardiovascular diseases, osteoporosis, Menopausal symptoms and other diseases.

Therapeutic uses : Isoflavones are naturally occurring non-steroidal compounds of plant origin found primarily in soya bean. These are classified as phytoestrogens and are beneficial in reducing the risk of hormones related problems.

• Inhibit tumour development.
• Plays an important role in reducing breast and prostrate cancer risk.
• Lowers the risk of coronary heart diseases.
• Prevents menopausal symptoms in women including hot flashes, night sweats, insomnia, mood swing, nervousness and irritability etc.
• Helps to prevent osteoporosis.

Standardisation : Soya Isoflavones are statndardized to 40% & 80%.

 Product Specifications:

S.No	Parameters	Specification
1	Description	Light Brown to Brown Coloured powder slightly hygroscopic
2	Identification	Respond to FeCl3 Reagent test-Bluish Black color
3	Loss on Drying (at 105 0C)	NMT 6% w/w
4	Ash content	NMT 5% W/W
5	Solubility in water alcohol	NLT 80% w/w NLT 80% w/w
6	Heavy Metals	NMT 20 PPM
7	Total Isoflavones By HPLC	NLT 40% w/w
8	Microbiological Profile :
	9.1 Total Plate Count	< 5000 cfu / g
	9.2 Yeast & Moulds	< 100 cfu /g
	9.3 Salmonella &E.Coli	Negative
	9.4 E.coli	Negative

Family : Theaceae

Plant parts used : Dried leaves

Chemical constituents : The active constituents in Camellia Sinensis, Green Tea are Polyphenols ( Catechins and flavonols).  Other constituents are caffeine and essential oil.

Pharmacology : The polyphenols in Camellia Sinensis, or Green Tea are catechins, with multiple linked ring-like structures.  The dominant and most important catechin in Green Tea is ( - ) epigallocatechin  Gallate ( EGCG) a potent anti-oxidant.  It protects against digestive and respiratory infections.  It helps to block cancer promoting actions of carcinogens ultraviolet light and metatasis. Green Tea also blocks the attachment of bacteria associated with dental caries to the teeth.  Green Tea polyphenols have been found to normalize thyroid hyperfunction which induces thyrotoxicosis.  It also prevents the formation of stones in bladder, liver and kidney.
 
Therapeutic uses: It is used as anti-oxidant, anticancer and anti-diabetic and for weight loss.  It reduces cholesterol and triglycerides.  It also reduces blood clotting.  Green Tea enhances immune function and improves dental health.

Standardistation : Green Tea extract is standardized to 50% & 95% Polyphenols / 20% & 45% EGCG.

Family : Asclepiadaceae

Plant Parts used :  Leaves

Chemical constituents : An organic acid called Gymnemic acid, said to be a glucoside, posses anti saccharine property. It is a complex mixture of at least 9 closely related acidic glycosides, the major active component being Gymnemic acid.

Pharmacology : The leaves of gymnema sylvestre have astringent stomachic, tonic and anti diabetic properties. The drug stimulates the pancreatic cells to the secretion of insulin and it also stimulates heart and circulatory systems. Recent clinical trial reports reveal that the extract of Gymenma leaves inhibits absorption of glucose in the small intestine and suppress the increase of blood glucose value.  It activates the uterus and increases urine secretion.  Gymnemic acids are useful for prevention of the formation of dental plaque and caries.

Therapeutic uses: Anti diabetic on account of the property of abolishing the taste of sugar. Gymnema Sylvestre has been given the name of 'Gurmar' meaning sugar destroying.

Standardisation : Gymnema sylvestre dry extract is standardized to 25%-75% Gymnemic acids.