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Gynae Care Products

We are leading Manufacturer & Service Provider for the Gynae Care Products which also includes Cranmed Capsule & FOL 123 Capsule since 2002

Cranmed Capsule

Composition: Each soft gelatin capsule contains-

Cranberry Extract (1:15)
(Standardized to contain Proanthocyanidins 15 mg,
200mg (26.32% w/w)
Polyphenols 50 mg & Anthocyanidins 30mg)  
D-Mannose 50 mg (6.57% w/w)

Action:

Cranberry (Vaccinium macrocarpon) has a long history of use in the treatment of urinary tract infections (UTIs). The cranberry extract is rich in polyphenolic compounds namely proanthocyanidins, which exhibit antimicrobial, anti-inflammatory and powerful antioxidant actions. Proanthocyanidins with A-type linkages from Cranberry prevent the growth, adhesion or biofilm formation of a large number of uropathogens which are responsible for causing UTIs. Proanthocyanidins in cranberry prevent the attachment of both type-1 and p-fimbriae. They also inhibit expression of types 1 and P-fimbiae.

D-mannose is a simple sugar form that occurs naturally in wood, fruits and the human body. It is a receptor for type 1 fimbriae in the uroepithelial cells. Thus, mannose covers fimbriae and brings about competitive blocking of fimbrial adherence. It also prevents hemagglutination. It also exerts osmotic diruretic action and helps flush the bacteria from the urinary tract.

Indications:

Recurrent and chronic UTI patients
Asymptomatic bacteriuria in pregnancy
Special Population (Uterine prolapsed, Stress incontinence, Bacterial vaginosis, IUD Insertion)

Dosage:
  • 1capsule b.i.d, for 10 days to 3 months.

FOL 123 Capsule

Composition: Each soft gelatin capsule contains-

Folic acid IP
5 mg
Vitamin B12 P 1 mcg
Docosahexaenoic acid (DHA) 200 mg

Action:
Folic acid is a member of the vitamin B group. Folic acid is reduced in the body to tetrahydrofolate, which is a coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence in the synthesis of DNA; it is also involved in some amino-acid conversions and essential for the remethylation of homocysteine into methionine which is further metabolized into S-adenosylmethionine, the universal methyl donor for transmethylation of DNA. By this way, it plays a key role in epigenetic regulation of gene expression. Folate deficiency, either by insufficient nutritional uptake or linked to some single nucleotide polymorphism, will lead to an impaired DNA synthesis and repair, a hypomethylation of DNA and other molecules, and homocysteine accumulation.

Vitamin B12, a water-soluble vitamin, occurs in the body mainly as methylcobalamin (mecobalamin) and as adenosylcobalamin (cobamamide) and hydroxocobalamin. Mecobalamin and cobamamide act as coenzymes in nucleic acid synthesis. Mecobalamin is also closely involved with folic acid in several important metabolic pathways. Deficiency leads to the development of megaloblastic anaemias, demyelination and neurological damage and may affect fertility.

Docosahexaenoic acid (DHA) is a long-chain unsaturated fatty acid that is a member of the omega-3 family of fatty acids. Docosahexaenoic acid plays an important role in brain and retinal development in infants. It is also the most abundant unsaturated fatty acid found in the brain. It is the predominant structural fatty acid in the central nervous system and retina and its availability is crucial for brain and neuronal development in infants. There is also evidence to suggest that depletion of maternal DHA reserves during pregnancy is an important correlate of postpartum depression.

Indications:
Preconception
Pregnancy
Lactation

Dosage:
1 capsule a day

Menoease Capsule

Composition: Each hard gelatin capsule contains-Soy isoflavones, Vitamins, Minerals and Trace Elements Capsules

Action:

Isoflavones are a class of phytoestrogens found predominantly in legumes and beans. Soybeans are a rich source of isoflavones and contain 2 to 4 mg of isoflavones per gram of protein. Isoflavones are heterocyclic phenols with structural similarity to estradiol-17 and selective estrogen receptor modulators. Soy protein is unique in that it is rich in polyunsaturated fats and fiber, which are cardioprotective, and also contains high amounts of the isoflavones genistein and daidzein, which have been postulated to act as estrogen agonists and antagonists.

Actions at the cellular level depend on the target tissue, receptor status of the tissue, and the level of endogenous estrogen. For example, in premenopausal women in whom circulating levels of endogenous estrogen are high, isoflavones may act as estrogen antagonists. In postmenopausal women with lower levels of circulating estrogen, the isoflavones may have the opposite effect and behave as estrogen agonists.

Indications:

  • Symptomatic management of Perimenopause Menopause Postmenopause
Dosage:
  • 1 capsule a day after meals.

QGold Capsule

Composition:

Ubidecarenone USP (Coenzyme Q10) 100 mg
Lycopene 5000 mcg
Omega-3 fatty acids containing:    
    Eicosapentaenoic acid (EPA) 90 mg
    Docosahexaenoic acid (DHA) 60 mg
Mixed carotene (10%) 10.33 mg
Wheat germ oil BP 25 mg
Calcium ascorbate USP 75 mg
Vitamin B12 IP 5 mcg
Selenium dioxide monohydrate USP 75 mcg
Zinc Sulphate Monohydrate 27.45 mg
Piperine 5 mg

Action:

Ubidecarenone (Coenzyme Q10)is a naturally occurring coenzyme involved in electron transport in the mitochondria. It is claimed to be a free radical scavenger and to have antoxidant and membrane stabilizing properties. Coenzyme Q10 [(CoQ10) also commonly called ubiquinone is present in well-measurable levels in human seminal fluid, where it probably exerts important metabolic and antioxidant functions; seminal CoQ10 concentrations show a direct correlation with seminal parameters (count and motility). Alterations of CoQ10 content were also shown in conditions associated with male infertility, such as asthenozoospermia and varicocele (VAR). Exogenous administration of CoQ10 increases both ubiquinone and ubiquinol levels in semen and can be effective in improving sperm kinetic features in patients affected by idiopathic asthenozoospermia.

Wheat germ oil, which is a rich source of natural vitamin E is also a potent antioxidant. Antioxidants such as vitamin C, vitamin E, glutathione, and coenzyme Q10, have proven beneficial effects in treating male infertility. 

Piperine is a standardized extract from the fruits of Piper nigrum L. (black pepper) or Piper longum L. (long pepper). Piperine may be co­administered with various nutrients for both human and animal health. Piperine exerts a host of physiological actions including enhancing digestive capacity, antioxidant activity, anti-imflammatory, anti-nociceptive, immunomodulatory and anti-tumor activities.

Indications:
  • Male infertility due to astheno,-teratozoospermia
Dosage:
  • 1 capsule / day.

Supracal Tablet

Composition:

Calcium Citrate USP 1000 mg
Magnesium Hydroxide IP equivalent to elemental Magnesium 100 mg
Zinc Sulphate Monohydrate USP equivalent to elemental Zinc 4 mg
Vitamin D3 IP 200 IU

Action:

Calcium is the most abundant mineral in the body and is an essential body electrolyte. Calcium supplementation has been shown to facilitate calcium retention and bone accrual in children and adolescents. In adults, it effectively promotes the consolidation and maintenance of bone mass. In conjunction with vitamin D, calcium supplementation also decreases bone fracture risk in the elderly, slows the rate of bone loss in old age, and is of benefit to the health and well-being of postmenopausal women. Calcium supplementation has long been regarded as a fundamental part of the prevention and treatment of postmenopausal bone loss.

Magnesium is the second most abundant intracellular cation in the body. Magnesium ion is a critical cofactor in more than 300 enzymatic reactions involving energy metabolism, and protein and nucleic acid synthesis. Accordingly, magnesium is essential for various normal tissue and organ functions.

Bone growth retardation is a common finding in various conditions associated with zinc deficiency, suggesting a physiological role of zinc in the growth and mineralization of bone tissue. Bone zinc content is decreased with aging, skeletal unloading, and postmenopausal conditions. Zinc has been demonstrated to have a stimulatory effect on bone formation and mineralization; the metal directly activates aminoacyl-tRNA synthetase in osteoblastic cells, and stimulates cellular protein synthesis. Moreover, zinc inhibits osteoclastic bone resorption by inhibiting osteoclast-like cell formation from marrow cells. Zinc may act on the process of bone-resorbing factors-induced protein kinase C activation, which is involved in Ca2+ signaling in osteoclastic cells. Thus, zinc plays a role in the preservation of bone mass.

Indications:

Hypocalcaemia
Calcium and vitamin D deficiency
Calcium deficiency during pregnancy and lactation
Rickets
Prevention of osteoporosis in postmenopausal women
Chronic renal failure

Dosage:
  • 1-2 tablets per day anytime

Suprafer (Tablets & Suspension)

Composition: Suprafer Tablets

Each film coated tablet contains:

Ferrous ascorbate    
Equivalent to elemental iron 100 mg
Folic acid IP 15 mg

Suprafer Suspension

Each 5 ml contains:
Ferrous ascorbate    
Equivalent to elemental iron 30 mg
Folic acid IP 500 mcg

Action:

Ferrous ascorbate is used as a source of iron for iron-deficiency anaemia.

Folic acid is a member of the vitamin B group. Folic acid is reduced in the body to tetrahydrofolate, which is a coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence in the synthesis of DNA; it is also involved in some amino-acid conversions, and in the formation and utilisation of formate. Deficiency, which can result in megaloblastic anaemia, develops when the dietary intake is inadequate (as in malnutrition), when there is malabsorption or there is increased utilization (as in pregnancy or conditions such as haemolytic anaemia), increased loss (as in haemodialysis), or as a result of the use of folate antagonists and other drugs that interfere with normal folate metabolism.

Indications:

Pregnancy & lactation
Iron deficiency anemia
Blood loss during surgery

Dosage:
  • Adults: 1 tab/day
  • Children: 5 mL twice daily.

To,Pharmed Limited

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