Each soft gelatin capsule contains-
|Folic acid IP||5 mg|
|Vitamin B12 P||1 mcg|
|Docosahexaenoic acid (DHA)||200 mg|
Folic acid is a member of the vitamin B group. Folic acid is reduced in the body to tetrahydrofolate, which is a coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence in the synthesis of DNA; it is also involved in some amino-acid conversions and essential for the remethylation of homocysteine into methionine which is further metabolized into S-adenosylmethionine, the universal methyl donor for transmethylation of DNA. By this way, it plays a key role in epigenetic regulation of gene expression. Folate deficiency, either by insufficient nutritional uptake or linked to some single nucleotide polymorphism, will lead to an impaired DNA synthesis and repair, a hypomethylation of DNA and other molecules, and homocysteine accumulation.
Vitamin B12, a water-soluble vitamin, occurs in the body mainly as methylcobalamin (mecobalamin) and as adenosylcobalamin (cobamamide) and hydroxocobalamin. Mecobalamin and cobamamide act as coenzymes in nucleic acid synthesis. Mecobalamin is also closely involved with folic acid in several important metabolic pathways. Deficiency leads to the development of megaloblastic anaemias, demyelination and neurological damage and may affect fertility.
Docosahexaenoic acid (DHA) is a long-chain unsaturated fatty acid that is a member of the omega-3 family of fatty acids. Docosahexaenoic acid plays an important role in brain and retinal development in infants. It is also the most abundant unsaturated fatty acid found in the brain. It is the predominant structural fatty acid in the central nervous system and retina and its availability is crucial for brain and neuronal development in infants. There is also evidence to suggest that depletion of maternal DHA reserves during pregnancy is an important correlate of postpartum depression.Indications:
1 capsule a day