Pharma & Cosmetics

The Mixing assembly consists of series of paddles types blades, pitched or flat, of appropriate shape. Here two consecutive blades move in opposite direction which creates laminar thinning of the material & facilitates uniform mix. Paddle type blades mounted on scrapping arms & welded to hollow shaft, have independent drive & has bottom support also. Paddles mounted on internal shaft creates relative movement of the material. Paddles mounted on internal shaft & hollow shaft rotates in anti-clockwise & clockwise direction respectively. The mixer is designed & fabricated to withstand perfect vacuum applied during the process for optimum mixing & to eliminate air entrapment as surfactant has tendency of forming suds. The vessel shall have a shell of suitable thickness with a hemispherical bottom and flanged top dish made out of S.S.304 plate. There is provision of bottom entry homogenizer in the same vessel which homogenizes all ingredients & hence there is no need to go for external inline homogenizer otherwise problem of aeration will increase process time. The vessel shall be suitable for 700mm vacuum and internal pressure of 3 kgs/CM2. There will be a suitable outlet provided for the product discharge.

We offer our esteemed clients quality-mixing vessels that find wide usage in different industries. It combines the quality and customization of pressure and/or process vessels with specialized in-tank or external mixing. Study in construction these vessels assist in most consistent product mixing. The unit of vessel range from simple clamp-on propeller units to multi-motion designs including counter rotation, scraped surface and high shear blending. The vessel application is carefully reviewed for sizing and selection and requires baffles for proper operations.

We offer the complete portfolio of homogenizer designed for pharmaceutical, life science, biotechnology, agricultural, microbiology and chemical research and development. These machines help in achieving uniform particle size by applying pressure and stress. Homogenizer are extensively used in pharmaceutical industry for manufacturing medicinal creams and lotions of required texture. The homogenizer ensure products with higher stability and longer shelf life.

Although new technologies like single-pot processing are becoming more and more important in pharmaceutical industry, the planetary mixer is still used for basic operations of mixing and blending. We offer a complete range of Collette planetary mixers, from lab-scale to large production machines, with all features and options that are required for flexible production. Our range of planetary mixers are in strict compliance with cGMP standards. These industrial planetary mixers are designed to be used in the pharmaceutical, food and fine chemical industries

Standard Features:

•   Stainless steel product contact parts 304 or 316.

•   Bowl trolley for easy transport.

•   Bowl cover incorporates filling aperture & inspection window.

•   Planetary movement provides very intensive, quick, homogeneous & dead-spot-free mixing.

•   Top driven design eliminates contamination through packing & seals.

•   Crank case design prevents oil leakage into bowl.

•   Removable bowl design and arm interchangeability allow easy cleaning and quick changeover.

•   Machine supplied as a complete unit only requires leveling and connection to electrical & air supply.

•   Robust construction.

•   Full interlocked guarding.

Capacity:

Standard models range from 50, 100, 250, 350, 500, 750, 1000 Kgs

 

We offer Ointment Manufacturing plants that are ideal for preparation of ointment cream

 

Features of Ointment Manufacturing Plant.

• Easily cleanable and completely untouched process, hence less chance of contamination.
• All contact parts made of Stainless Steel 316 and non contact part ss 304 material.
• All pipelines are electro polished from inside and joints are easy openable.
• Complete cover lifting arrangement to facilitate cleaning at the time of product change over.
• Especially semi-contra & Double contra designed anchor stirrer with flexible Teflon scrapers.
• The plant is provided with pre-mixing wax and water phase vessels and the main manufacturing vessel.
• The main vessel is provided with a slow speed anchor agitator for mixing and a bottom high speed homogenizer for emulsifying.
• Variable speed drive provided for main anchor stirrer assembly for different speeds
• Jacketed vessels for heating/cooling processes.
• Inspection glass with illumination.

         Specially designed inline filters can also be   provided to ensure proper filtration
Optional Requirement are :

    --- Load cell for accurate weighing.

    --- PLC based control panel for process     automation

    --- Contra type agitator for calcium base toothpaste.

•  The Ointment Manufacturing Plant/Cream Manufacturing Machine is suitable for        manufacturing pharmaceutical ointments, sterile preparations, cosmetic creams, suspensions, gels, etc.

Equipments of Ointment Manufacturing Plant.

• Wax heating Vessel.
• Water Melting Vessel.
• Manufacturing vessel.
• Storage vessel.
• Interconnecting pipeline.
• Pumps -Lobe Pump and metering pumps.
• Integrated automatic control panel.
• Working Platform.

 

Capacity:

Standard models range from 50, 100, 250, 350, 500, 750, 1000, 1500, 2000, 2500 Kg

 

We are engaged in the manufacture of Contra Rotary Mixture used for the manufacture of ointments. The mixture contains double contra rotary blades that create a laminar thinning of the material to ensure uniform mixing.

 

The mixture is enriched with the following unique features:

• Vacuum Operated
• Agitated
• Jacketed suitable for Steam heating

 

The design of the mixer is perfect to withstand the vacuum created during the process of mixing. Further, these also eliminate air entrapment to prevent the foaming agent from forming suds. Mixer is provided with jacket for cooling or heating as per the application.

Catering to the demand of chemical plants, these precision engineered pilot plants are attuned to international quality standards. These pilot plants are fabricated by us using highest grade of rust proof materials, that make them highly durable in quality. Our pilot plants are characterized by precise dimension, high tensile strength and superior functionality. We can custom design them in compliance with specifications of our clients.

Operation :

The unfiltered liquid is fed into the filter under positive pressure, where liquid travels in downwards direction and finds its way through opening on sides of the Filter Plates.

As the liquid pressure increases, the Filter media holds the foreign particles and allows only clear filtrate to pass through the central channel formed by interlocking pressure cups to the outlet. Filtration is continued until the cake holding capacity of the unit is reached or until the filtrate rate becomes too slow owing to cake resistance.

 

Sparkler Filter Press Features :

• Horizontal Plate / Sparkler Filter Press is enclosed construction, preventing evaporation, oxidation, leakage and fumes escaping from product.
• Sparkler Filter plates are available in two sizes. Deep plate for large percentage of cake holding capacity and Shallow plate for small percentage of cake holding capacity.
• In the Sparkler Filter Press, The horizontal filter plate and even thickness of cake, prevents the cake dropping as well as cracking, thus assuring better filtrate quality.
• The Filtration area and cake holding capacity can be increased or decreased according to requirement. 

Capacity:

Standard Model range from 400, 500, 1500, 1800, 2500, 4500, 3700, 6800, 6700, 12600, 8000 to 15000 Ltrs.

The Liquid Manufacturing Plants are ideal tools for the pharmaceutical industry for the production of Oral Liquids. It is specially designed to take care of two critical factors which directly affect the quality of the Liquids. Minimum manual handling of Liquid.

Effective cleanness during manufacturing. Capacity ranges from 50 L to 20,000 L.

Needless to say, it also provides the benefits of the effective manpower utilization.

Liquid Manufacturing Plant consists : -

• Sugar Melting Vessel
• Pre-filtration unit
• Syrup Manufacturing Vessel
• Filtration unit
• Storage Vessel
• Control Panel
• Product Piping
• Working Platform

• This system consists of a closed circuit manufacturing facility from feeding of Sugar / Water Phase to loading the Liquid
  Filling Machine.
• The Sugar and Water, are load with vacuum system or by mechanical system or manually.
• The Sugar Syrup Vessel is supplied with high speed stirrer steam heating facility.
• The product during emulsion formation is recalculated through In-Line Homogenizer or Liquid Transfer Pump.( Optional Facility )
• The Pump also discharges the product in the Storage Vessel.
• The Storage Vessel is then taken to the filling area (if it is small capacity) and is connected to again Liquid Transfer
  Pump. Or Storage Vessel remains fixed (In bigger size) & pump transfer the Liquids in the float tank which is connected
  with filling machine.
• The entire Plant can be operated by centralized operating panel by one operator.

Salient Features :

• The Plant is designed to be operated only by one operator and one helper.
• All material transfers are done by vacuum or by transfer pumps.
• All the vessels are CGMP (paint free construction)
• The gaskets used are of silicon (food grade).
• All contact parts are of S.S. 304 quality material (SS316 provided on demand) & finished to class 4B (Mirror) finish and
  are crevice free.
• The entry of stirrer & high speed emulsifier are from top. In-line Emulsifier (as per customer choice) provided on
  demand.
• All vessels are suitable for internal pressure of 1.5 Kg. / Sq. cm. and hence can be sterilized.
• All pipes, pipe fittings and valves are of SS304 / SS316 (as per customer requirement) seamless quality, internally
  electro polished, with tri-clover ended joints.