|piosys belongs to the class of anti-diabetic drugs called "thiazolidinediones" that are used for the management of type ii diabetes mellitus.|
|mechanism of action||piosys decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. Unlike sulfonylureas, pioglitazone is not an insulin secretagogue. |
pioglitazone is a potent agonist for peroxisome proliferator-activated receptor-gamma (pparγ). Ppar receptors are found in tissues important for insulin action such as adipose tissue, skeletal muscle, and liver.
activation of pparγ nuclear receptors modulates the transcription of a number of insulin responsive genes involved in the control of glucose and lipid metabolism.
|indication||in type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus, niddm)|
|dosage||piosys monotherapy is given in patients not adequately controlled with diet and exercise may be initiated at 15 mg or 30 mg once daily. For patients who respond inadequately to the initial dose of piosys, the dose can be increased in increments up to 45 mg once daily.|
|side effects||edema , weight gain , anemia (1%) , myalgia (3%) , headache, hepatotoxicity (rare), fracture of bone, macular retinal edema|
|sales pack||piosys : pack of 100 tabs/ box (10 x 10)|
The name Systopic denotes Systemic and Topical therapies. Systopic is one of the most scientific companies in the Indian pharma market. The company has been providing innovative products aimed to deliver better therapeutic solutions.
The strength of the company has been its scientifically oriented marketing field force of 640 committed people & more than 70000 customer base who hold the company in high esteem and also make it a force to reckon within the Indian Pharmaceutical Industry.
Our speciality focused customer base of Orthopedicians, Gastroenterologists, Gynecologists, Dermatologists, Cardiologists, Surgeons and others are serviced through a marketing network of strong field force which also includes frontline managers as well as various field management cadres.
In fact, our well trained and up to date field personnel represent the company's innovative products to the customers and are in a way the pride of the company. The company has strong people development programmes and a commitment to promotion from within.
Thus our mission statement of
Systopic Laboratories Private Limited
No. 101, Pragati Chambers Commercial Complex, Ranjit Nagar
New Delhi - 110008 Delhi, India
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Sofosbuviris a prescription Medicine used with other antiviral Medicines to treat chronic ( lasting a long time ) Hepatitis c ( Hep c ) infection in adults.