Zeal Medichem

Atorvastatin (INN) (pronounced /əˌtɔrvəˈstætən/), sold by Pfizer under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissuethat plays a key role in production of cholesterol in the body.

Systematic (IUPAC) name
(3R,5R)-7-[2-(4-fluorophenyl)- 3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)- 1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
Identifiers
CAS number	134523-00-5
ATC code	C10AA05
PubChem	CID 60823
DrugBank	APRD00055
ChemSpider	54810
UNII	A0JWA85V8F
KEGG	D07474
ChEMBL	CHEMBL1487
Chemical data
Formula	C33H35FN2O5
Mol. mass	558.64
SMILES	eMolecules & PubChem
InChI[show]
Pharmacokinetic data
Bioavailability	12.00%
Metabolism	Hepatic - CYP3A4
Half-life	14 h
Excretion	Bile