Beclometasone dipropionate (INN modified) or
beclomethasone dipropionate (USAN, former BAN), also referred to as
beclometasone (INN), is a potent glucocorticoid steroid. In the form of an inhaler (e.g. Clenil, Qvar), a wide number of brands of which are available, it is used for the prophylaxis of asthma. As a nasal spray (e.g. Beconase, alanase, Vancenase), it is used for the treatment of rhinitis (e.g. hayfever) and sinusitis. In some instances it is used by oral pathologists in the treatment of unusually severe aphthous ulcers.
| ATC code | A07EA07 D07AC15, R01AD01,R03BA01 |
| PubChem | CID 21700 |
| DrugBank | APRD00564 |
| ChemSpider | 20396 |
| UNII | 5B307S63B2 |
| Chemical data |
|
| Formula | C28H37ClO7 |
| Mol. mass | 521.042 g/mol |
| SMILES | eMolecules & PubChem |
| Bioavailability | Converted to beclometasone-17-monopropionate (17-BMP) during absorption |
| Protein binding | 87% of 17-BMP to albumin and transcortin |
| Metabolism | By esterase enzymes found in most tissues |
| Half-life | 2.8 hours |
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