Farlex Pharmaceuticals Private Limited

Methylcobalamin is one of two coenzymes forms of B12. Evidence indicates that methylcobalamin has some metabolic and therapeutic applications not shared by the other forms of vitamin B12. Cyanocobalamin, the second coenzyme, is the most common form of B12 provided at physician offices and in over the counter supplements. Methylcobalamin is the more bio-available of the two, meaning that methylcobalamin is immedietly ready for the body to use once injected. Cyanocobalamin must be first broken down within the liver only to produce small amounts of methylcobalamin which the body can utilize.

Methylcobalamin is a very effective treatment for B12 deficiencies commonly found in patients suffer from disease or have nutritional deficits (such as ultra low calorie diets).

Methylcobalamin is the only active form of B12 found within the Central Nervous System (CNS). Benefits of Methylcobalamin supplementation include:

• Assists in the reduction of elevated Homocysteine. Elevated Homocysteine has been linked to increased cardiovascular risk of disease.
• Proven beneficial for symptoms of depression (i.e., supporting the production of serotonin and melatonin)
• acts as a methyl donor and participates in the synthesis of SAM-e (S-adenosylmethionine), a nutrient that has powerful mood elevating properties.
• Supports Immune system regulation
• Repair of damaged myelin sheath
• acts to reverse nerve damage and promote nerve cell regeneration
• Increased metabolic function
• Supports healthy red blood cells and is used to treat Anemia
• Protects against neurological disease and aging
• Improvement of mental dysfunction in the elderly
• Supportive treatment in HIV
• Useful in protocols for asthma and sulfite sensitivities
• necessary for the conversion of methylmalonate to succinic acid, an important Krebs cycle intermediate in energy production

Methylcobalamin is a water based vitamin and is very easy to inject using a small "insulin" needle. Methylcobalamin is stored in the body for long periods of time and serum B12 levels in most healty people can remain elevated for up to one month after a single injection. Methylcobalamin is a water soluble vitamin and high dosages can be taken without risk, therefore many people take more frequent injections to help with energy. Here is one recommended protocol for taking methylcobalamin injections:

Using a small "insulin" syringe, measuring 5/16" to 1/2", inject subcutaneously 1ml of methylcobalamin once per week. It can be taken additional days in between weekly injections if you feel there is a benefit or if you require more frequent injections to treat chronic illness. Some people take methylcobalamin daily to treat certain symptoms.

Serum B12 Level Maintenance

Optimal serum B12 levels can be maintained with methylcobalamin injections administered once per month. It is recommended to inject methylcobalamin deeper when administering less frequent injections. We recommend using a 5/8" to 1" needle when injecting methylcobalamin once per month. Here is a good protocol if your goal is to treat B12 deficiency and bring serum B12 levels to a good range:

• For single use only
• For IV infusion only

Additional Information:

• Packaging Details: Single Vial with WFI

• Ceftriaxone is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using ceftriaxone at home, a health care provider will teach you how to use it. Be sure you understand how to use ceftriaxone. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Ceftriaxone is light yellow to amber in color. Do not use ceftriaxone if it contains particles, is cloudy or discolored, or if the vial or container is cracked or damaged in any way.
• To clear up your infection completely, use ceftriaxone for the full course of treatment. Keep using it even if you feel better in a few days.
• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
• If you miss a dose of ceftriaxone, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ondansetron treats and prevents nausea and vomiting by an unknown mechanism, possibly by a direct effect on the CTZ (the area of the brain associated with vomiting) or the vagus nerve or both. The neurotransmitter, serotonin, appears to play a role in ondansetron's effect.

For IM/IV use only.