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Green Signal Bio Pharma Pvt. Ltd

United India Colony, Chennai, Tamil Nadu

| GST  33AACCG4791M1ZA

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BCG Vaccine

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Urovac Injection

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Green Signal Bio Pharma Pvt. Ltd - Manufacturer of bcg vaccine, urovac (bcg onco bp vaccine) in Chennai, Tamil Nadu.+ Read More

Nature of Business

Manufacturer

Legal Status of Firm

Limited Company (Ltd./Pvt.Ltd.)

Annual Turnover

Rs. 25 - 50 Crore

GST Number

33AACCG4791M1ZA

BCG Vaccine
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BCG Vaccine

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BCG or Bacillus Calmette Guerin is a vaccine used for prevention of Tuberculosis(TB) in humans since 1921.Approximately 100 million children were administered (vaccinated) with BCG in almost 170 countries in the world.The BCG vaccine is prepared from a strain of attenuated,live tuberculosis bacilli' Mycobacterium Bovis. That has lost it's virulence in humans by being specially cultered in an artificial medium for years.The bacilli have retained enough strong antigenecity to become an effective Vaccine for the prevention of tuberculosis in human beings.

BCG Vaccine is one of the most widely used vaccines in the world. Its efficacy against TB meningitis in the pediatric age-group is established; but its efficacy against pulmonary TB is appears to be variable. Many countries use BCG for prevention of TB. But a few countries like U.S, they do not use BCG for routine vaccination. This is probably because they believe in detecting the active disease by a reliable Mantoux test, instead of practicing the routine vaccination against a relatively rare condition i.e, the incidence of TB is very low.

Efficacy:-The most controversial aspect of BCG is its variable efficacy when used in various clinical trials. This appears to depend on the geography. The efficacy of 14% to 84% upto 5 years after immunization. However a clinical trials conducted in South India showed no protective effect.

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UROVAC (BCG ONCO BP Vaccine)
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 UROVAC - BCG ONCO BP (Intravesical) is a live freeze-dried preparation made from Bacillus Calmette-Guerin strain, which is an attenuated strain of Mycobacterium bovis. The BCG is propagated as a live attenuated strain obtained as a primary seed (Strain ' Danish 1331). Bacillus Calmette-Guerin (BCG) immunotherapy has been widely accepted as the optimal treatment for carcinoma in situ and high grade superficial transitional Urinary Bladder Carcinoma. It is not intended as an immunizing agent for the prevention of tuberculosis. UROVAC - BCG ONCO is not a vaccine for the prevention of cancer.

Composition: Each vial contains 40 mg of BCG, having 1 - 8 x 108 CFU. 5% Sodium glutamate is used as the stabilizer. Reconstitute each vial with 50 mL of Sodium Chloride (0.9% w/v) injection.

Indications: Carcinoma in situ of urinary bladder prophylaxis and treatment, BCG is used intravesically for prophylaxis and treatment of primary multifocal, high grade and relapsed superficial transitional bladder carcinoma. It is used to reduce the frequency of tumor recurrence after transurethral resection and to eliminate existing tumors, including Ta and T1 tumors and carcinoma in situ (CIS tumors) with or without associated papillary tumors. It is not indicated for the treatment of papillary tumors occurring alone or for prevention of papillary tumors after transurethral resection.

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BCG Vaccine

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Urovac Injection

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Bacillus Calmette Guerin

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