Konar Organics Limited

Niclosamide is used to treat broad or fish tapeworm, dwarf tapeworm, and tapeworm infections. Niclosamide may also be used for other tapeworm infections as determined by your doctor. It will not work for other types of worm infections (for example, pinworms or roundworms)

Niclosamide works by killing tapeworms on contact. The killed worms are then passed in the stool. However, you may not notice them since they are sometimes destroyed in the intestine.

Test Specification
Description : A white crystalline Powder
Clarity and colour of solution : The Solution is Clear and Colourless.
Identification : As per standard specification
» By IR : The Infra red absorption spectrum of the sample should exhibit maximum only at the same wavelengths as that of a similar preparation of FLUCONAZOLE working standard
Melting Range : 138ºC - 142ºC
Loss On Drying : NMT 0.50%
Residue on Ignition : NMT 0.10%
Iron Content : NMT 0.002%


Related Compounds (Test - 1)

» Impurity at RRT 0.6 : NMT 1.00%
» Impurity at RRT 0.5 or 0.9 : NMT 0.20%
» Any other individual Impurities : NMT 0.10%
» Total Other impurity : NMT 0.20%
» Total Impurities : NMT 1.20%
Assay by Chemical : NLT 98.00 % and NMT 102.00 %

an anthelmintic used mostly in domestic animals, it is used as a dewormer for cattle, sheep, horse, pig, dog, camel, deer and ostrich etc.
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It is highly effective against itch-mite, mange, fascioliasis, sheepnose fly, cowskin fly, fascioliasis, gastrointestinal nematode and demodicidosis etc.

Test Specification
Description : White or almost white crystals or crystalline powder.
Solubility : Freely soluble in water and in ethanol (96%); slightly soluble in glycerol and in liquid paraffin.
Identification : A. The infrared absorption spectrum, is concordant with the reference spectrum of bronopol (RS 031).

B. Dissolve 0.1 g in 10 ml of water , add 10 ml of 7.5M sodium hydroxide and, carefully with constant stirring and cooling, 0.5 g of nickel-aluminium alloy. Allow the reaction to subside, filter and carefully neutralise with nitric acid. The resulting solution yields reaction A characteristic of bromides,

C. Melting point, after drying over phosphorus pentoxide at a pressure not exceeding 0.7 kPa, about 130 ºC
P H : Between 5.0 to 7.0
Sulphated Ash : NMT 0.10 % w/w
Water : NMT 0.50% w/w
Related substances by HPLC
» Single Impurity :

NMT 0.50%
» Total Impurities : NMT 1.00%
Assay (on anhydrous basis) : NLT 99.0% and NMT 101.0%