Landmark Pharma

Uses:

• enzalutamide is used to treat men with a certain type of prostate cancer. This type of prostate cancer has not responded to other treatments to lower the male hormone and has also spread to other parts of the body. This medication belongs to a class of drugs known as anti-androgens. It works by blocking the effects to slow the growth and spread of prostate cancer.

How Enzalutamide Works:

• enzalutamide is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Side Eeffects:

• hot flashes, headache, dizziness, or decreased interest/ability may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
• remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
• tell your doctor right away if you have any serious side effects, including: back pain, numbness/tingling/weakness/pain of the arms or legs, falls, broken bones, pink/red urine.

Precautions:

before taking enzalutamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

• Purity
• Longer shelf life
• Hygienic packaging

Uses:

This medication is used to treat certain types of brain cancer. Temozolomide belongs to a class of drugs known as alkylating agents. It works by slowing or stopping the growth of cancer cells.

How to Use Temodar:

• Read the Patient Information Leaflet if available from your pharmacist before you start taking temozolomide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
• Take this medication by mouth as directed by your doctor, usually once a day on a treatment schedule. Swallow the capsules whole with a full glass of water (8 ounces or 240 milliliters). Do not crush, chew, or open the capsules. If you vomit after taking your dose, do not take any more medication. Wait and take your next dose at the regular time. To reduce nausea and vomiting, take temozolomide on an empty stomach or at bedtime. For the best effect, take this medication at the same time every day in relation to a meal (for example, 1 hour before or 3 hours after a meal).
• The dosage and treatment schedule are based on your medical condition, height, weight, and response to treatment. Carefully follow your doctor's directions for taking this medication. To help you remember, mark your calendar to keep track of when to take the next dose.
• Your doctor may also prescribe other medications (such as antibiotics) to help prevent infection or side effects. Follow your doctor's directions for taking all your medications.
• Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.
• If the capsules are accidentally opened or damaged, avoid inhaling the medication or getting it on your skin. If contact occurs, flush the area with water. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

Side Effects:

Nausea, vomiting, loss of appetite, mouth sores, changes in taste, constipation, tiredness, dizziness, trouble sleeping, or headache may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Precautions

• Before taking temozolomide, tell your doctor or pharmacist if you are allergic to it; or to dacarbazine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, bleeding/blood problems.

• Bitter and odorless
• Stable salts stay long time in blood
• Better recovery

Enriched by our vast industrial experience in this business, we are involved in offering an enormous quality range of Clokeran Chlorambucil Tablets.

• Purity
• Effectiveness
• Precise pH value

• Accurate composition
• Purity
• Perfectly processed

Used:

It is used in the treatment of intermediate or high-risk myelofibrosis, a type of myeloproliferative disorder that affects the bone marrow, and for polycythemia vera (PCV) when there has been an inadequate response to or intolerance of hydroxyurea.

Mechanism of action:

Capegard 500mg Tablet is a Janus kinase inhibitor with selectivity for subtypes JAK1 and JAK2 of this enzyme. Ruxolitinib inhibits dysregulated JAK signaling associated with myelofibrosis. JAK1 and JAK2 recruit signal transducers and activators of transcription (STATs) to cytokine receptors leading to modulation of gene expression.

Dosage and Administration:

 Capegard 500mg Tablet is a pill, taken by mouth, with or without food. Take ruxolitinib exactly as prescribed, even if you are feeling better. Swallow ruxolitinib tablets whole. Do not chew, crush or break.

Side Effects:

Side effects include thrombocytopenia (low blood platelet count), anemia (low red blood cell count) and neutropenia; risk of infection; symptom exacerbation if the medication is interrupted or discontinued; and non-melanoma skin cancer.

Immunologic side effects have included herpes zoster (shingles) and case reports of opportunistic infections. Metabolic side effects have included weight gain. Laboratory abnormalities have included alanine transaminase (ALT) abnormalities, aspartate transaminase (AST) abnormalities, and mildly elevated cholesterol levels.

Precaution:

Capegard 500mg Tablet may interact with many types of medications . Before starting ruxolitinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).

Do not receive any kind of immunization or vaccination without your doctor''s approval while taking ruxolitinib.

Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category C (use in pregnancy only when benefit to the mother outweighs risk to the fetus).

Store:

Store Capegard 500mg Tablet at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep abiraterone acetate out of the reach of children and away from pets.

Capecitabine Tablets USP 500 mg

Meeting the demands of patrons as an exporter, distributer, trader and supplier, we are engaged in presenting

Revolade Tablet:

Provided tablets are developed by using quality assured chemical material and leading technology. Along with this, our offered tablets are given in attractive packaging options according to the clientele needs & demands. These tablets are tested for its quality & purity on given list quality parameters by our specialist.

Features:

Accurate compositionLonger shelf lifePrecisely processed

• This drug is used with other HIV medications to help control HIV infection.
• It helps to decrease the amount of HIV in your body so your immune system can work better.
• This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

• Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA.
• Unlike nucleoside RTIs, which bind at the enzyme''s active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.
• Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

• Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
• This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Talk to your pharmacist for more details.

Store:

• Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C).
• Store in a tightly closed container away from heat, moisture, and light.

• Temper proof packing
• No side effects
• Safe packaging

Indication:

It is the first therapeutic proteasome inhibitor to be tested in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly. Bortezomib interrupts this process and lets those proteins kill the cancer cells. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.

Mechanism of Action:

The boron atom in bortezomib binds the catalytic site of the 26S proteasome^] with high affinity and specificity. In normal cells, the proteasome regulates protein expression and function by degradation of ubiquitylated proteins, and also cleanses the cell of abnormal or misfolded proteins. Clinical and preclinical data support a role in maintaining the immortal phenotype of myeloma cells, and cell-culture and xenograft data support a similar function in solid tumor cancers.

Dosage and Administration:

Use bortezomib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Drinking extra fluids while you are taking bortezomib is recommended. Check with your doctor for instructions.
• Bortezomib is given as an injection into a vein or under the skin at your doctor''s office, hospital, or clinic. Bortezomib is not intended to be injected into the spinal cord. Contact your health care provider if you have any questions.
• It is very important that each dose is given at the scheduled time. If you miss a dose of bortezomib, contact your doctor right away to establish a new dosing schedule. Do not use 2 doses at once.
• Ask your health care provider any questions you may have about how to use bortezomib.

Side Effects:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache; loss of appetite; mild stomach pain; nausea; stomach upset; taste changes; tiredness; trouble sleeping; vomiting; weakness.

Precaution:

• Bortezomib may cause dizziness, fatigue, fainting, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use bortezomib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Bortezomib may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Store:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.Keep out of the reach of children.Do not keep outdated medicine or medicine no longer needed.
Bortezomib For Injection

We have achieved a distinct position in the market by trading, exporting, importing, distributing and supplying a superior quality Temonat Capsules. Used in treatment of gastrointestinal stromal tumors, offered capsules are hygienically processed using the best quality chemical compounds and modern technology under the vigilance of vendors’ professionals. Furthermore, these capsules are tested on varied parameters by our quality examiners so as to ensure their quality. We are offering these capsules in various packing options at pocket friendly prices.

Features:

• Used for brain cancer
• Highly effective
• No side effects

Indication:

It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.

Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

Mechanism of Action:

The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O⁶-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide) .

• This medication is given in a capsule form by mouth.
• Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
• Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
• The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Side Effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.

Precaution:

• Before starting Temonat (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Temonat (Temozolomide) .
• Let your health care provider know if you've had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

Store:

Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.