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Landmark Pharma

CBD Belapur, Mumbai, Maharashtra

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Anti Cancer Medicines

Prominent & Leading Exporter from Mumbai, we offer Sorafenat Tablets, Bortecad Injection, Clokeran Chlorambucil Tablets, Temonat Capsules and Xbira Tablets.

Sorafenat Tablets
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Sorafenat Tablets

Rs 200 / StripGet Latest Price

Dose/Strength600 mg
BrandCipla
Packaging Size30 Tablets
Other NameEfavirenz Tablets IP

Specifications:

  • Efavir (Efavirenz)
  • Brand name: Efavir
  • Active Ingeridents(Generic Name) : Efavirenz
  • Company Name: Cipla

Indication:

  • This drug is used with other HIV medications to help control HIV infection.
  • It helps to decrease the amount of HIV in your body so your immune system can work better.
  • This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

 

Mechanism of action:

  • Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA.
  • Unlike nucleoside RTIs, which bind at the enzyme''s active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.
  • Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

 

Precaution:
  • Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
  • This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • Talk to your pharmacist for more details.

 

Store:

  • Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C).
  • Store in a tightly closed container away from heat, moisture, and light.
Efavirenz Tablets IP

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Sorafenat Tablets
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Sorafenat Tablets

Rs 7,000 / BottleGet Latest Price

Packaging TypeBottle
BrandNatco
Packaging Size120 Tablets
Other NameSorafenib Tablets IP

Our enterprise is widely engrossed in providing an impeccable quality Sorafenat Sorafenib Tablets. The offered tablets are processed using optimum quality chemical compounds and advanced technology at vendors’ end in tandem with industry norms. In order to maintain their quality, these tablets are tested under the guidance of our quality examiners. Apart from this, we provide these tablets in different packaging forms in accordance to the demands of our clients.

Features:

  • Accurate composition
  • Highly effective
  • No side effects


Specifications: 


  • Available in: 200 mg and 120 Tablet
Sorafenib Tablets IP

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Bortecad Injection
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Bortecad Injection

Rs 12,000 / VialGet Latest Price

Packaging TypeGlass Bottle
Dose/Strength (ex. 1 mg or 1 ml)2mg
UsageClinical
BrandCadila

Indication:

It is the first therapeutic proteasome inhibitor to be tested in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly. Bortezomib interrupts this process and lets those proteins kill the cancer cells. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.

Mechanism of action:

The boron atom in bortezomib binds the catalytic site of the 26S proteasome] with high affinity and specificity. In normal cells, the proteasome regulates protein expression and function by degradation of ubiquitylated proteins, and also cleanses the cell of abnormal or misfolded proteins. Clinical and preclinical data support a role in maintaining the immortal phenotype of myeloma cells, and cell-culture and xenograft data support a similar function in solid tumor cancers.

Dosage and Administration:

Use bortezomib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Drinking extra fluids while you are taking bortezomib is recommended. Check with your doctor for instructions.

· Bortezomib is given as an injection into a vein or under the skin at your doctor's office, hospital, or clinic. Bortezomib is not intended to be injected into the spinal cord. Contact your health care provider if you have any questions.

· It is very important that each dose is given at the scheduled time. If you miss a dose of bortezomib, contact your doctor right away to establish a new dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use bortezomib.

 

Side effects:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache; loss of appetite; mild stomach pain; nausea; stomach upset; taste changes; tiredness; trouble sleeping; vomiting; weakness.

 Precaution:

· Bortezomib may cause dizziness, fatigue, fainting, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use bortezomib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

· Bortezomib may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

 Store:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.Keep out of the reach of children.Do not keep outdated medicine or medicine no longer needed.
Bortezomib For Injection 

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Clokeran Chlorambucil Tablets
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Clokeran Chlorambucil Tablets

Rs 2,500 / BottleGet Latest Price

Packaging Size30 Tablets
Packaging TypeBottle
BrandNatco
Other NameChlorambucil Tablets

Enriched by our vast industrial experience in this business, we are involved in offering an enormous quality range of Clokeran Chlorambucil Tablets.

Chlorambucil Tablets IP

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Temonat Capsules
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Temonat Capsules

Rs 9,700 / StripGet Latest Price

Dose100 mg
Packaging Size5 Capules
BrandNatco
Other NameTemozolomide Capsule

We have achieved a distinct position in the market by trading, exporting, importing, distributing and supplying a superior quality Temonat Capsules. Used in treatment of gastrointestinal stromal tumors, offered capsules are hygienically processed using the best quality chemical compounds and modern technology under the vigilance of vendors’ professionals. Furthermore, these capsules are tested on varied parameters by our quality examiners so as to ensure their quality. We are offering these capsules in various packing options at pocket friendly prices.


Features:


  • Used for brain cancer
  • Highly effective
  • No side effects
Temozolomide Capsule

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Temonat Capsules
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Temonat Capsules

Rs 23,000 / PackGet Latest Price

Packaging TypeBottle
Packaging Size5 Capsules
BrandNatco
Other NameTemozolomide Capsules

Indication:

 

It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.

Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

 

Mechanism of action:

The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O6-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide) . 

 

 

Dosage and Administration:

  • This medication is given in a capsule form by mouth.
  • Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
  • Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
  • The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

 

Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.

 

Precaution:

 

  • Before starting Temonat (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing aspirin unless your doctor specifically permits this.
  • Do not receive any kind of immunization or vaccination without your doctor's approval while taking Temonat (Temozolomide) .
  • Let your health care provider know if you've had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

 

Store: Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.\

Temozolomide Capsules IP

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Xbira Tablets
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Xbira Tablets

Rs 18,000 / BottleGet Latest Price

Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)250 mg
FormTablets

We are engaged in trading, distributing, exporting and supplying Pharmaceutical Products like Xbira tablets.

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