Makronix Life Sciences Private Limited

TELMISARTAN:-
It's shows equal benefits in composite endpoint of CV death, MI, stroke, CHF hospitalization & organ protection
Has lower rates of cough & angioedema,hence lesser side effects & better tolerated than ramipril.
AMLODIPINE:-
Gradual onset of therapeutic action
No fluctuations in B.P
Control During vulnerable morning hourse
Spares sudden cardiac episodes or myocardial ischemia
INDICATIONS:-
Patients with mild to severe hypertension
Diabetics & elderly hypertensives

Addition of health supplements is a boost in cardiovascular & immuno deficiency disorders.
Activate glucose metabolism for control of diabeties.
Ensure remethylation of myelin sheath & repairs damaged nerve fibres .
Scavenges free radicals & relives physical & mental stress.
Prevents & treats deficiency diseases.
Prevents macular degeneration in eye.
Supports muscle functions
INDICATION:-
Adjuvant therapy to diabetes
Cardiac disorders
General debility
Convalescence
Adjuvant to antibiotics
Dementia
Liver dysfunction
Alcoholism

TELMISARTAN:-
The unique with cardiometabolic effacts.
Improves insulin resistance in hypertensive & type 2 diabetics.
HYDROCHLOROTHIAZIDE:-
Increases excretion of sodium and chloride.
Treats hypertension and edema.
Reduces the amount of water.
Mild to moderate hypertension
Hypertension with diabetes

An antidiabetic with least risk of hypoglycemia
Decreases HbA1c by 1.2- 1.9% in patients with type 2 diabetes mellitus, which is not sufficiently controlled by diet and exercise.
Increase peripheral glucose utilization by 29%.
Potentially active in lowering risk factors of atherosclerosis in type 2 diabetic patients.
INDICATION:-
Initial management of type-2 diabetes
Uncontrolled diabetics

An antidiabetic with least risk of hypoglycemia.
Decrease HbA1c by 1.2- 1.9% in pqtients with type 2 diabetes mellitus, which is not sufficiently controlled by diet and exercise.
Increases peripheral glucose utilisation by 29%.
Potentially active in lowering risk factors of atherosclerosis in type 2 diabetic patients.
INDICATIONS:-
Initial management of type -2 diabetes.
Uncontrolled diabetes.

• TYRAB-DSR, Rabeprazole 20mg and Domperidone 30mg

• TYRAB-DSR, Rabeprazole 20mg and Domperidone 30mg

Specially active against beta-lactamase prodicing strains of H. Influenza and N. Conorrhoea
Excellent efficacy against major respiratory pathogens and rapid bacteriocidal response.
Adequate and uniform distribution in inflamed bronchial and sinus mucosa
Septicemia
Pharyngitis
Tonsillitis
Meningitis
UTI & LRTI
Joint infections

Olmike Effective controls BP compared to Losartan.
Olmike Helps in lowering high blood pressure helps prevent strokes, heart attacks
Olmike is better than telmisartan in treating cardiac patients with diabeties.
SYMPTOMS:-
Screening
Headache
Anxiety
Fainting Episodes
Hypertensive retinopathy
Treat hypertension with olmike for healthy mind

Reduces blood glucose more rapidly than glipizide over first few weeks of treatment.
Pharmaceutics are unaltered in elderly patients or those with renal or liver disease.
Glimepiride may contribute to overcome insulin resistance.
Improves peripheral and hepatic sensitivity to insulin.
Significant reduction in GI side effects.

CALCIUM CARBONATE:-
Cures all problems associated with hypocalcaemia. 
CALCITRIOL:-
Helps in the absorption of calcium from the gastrointestinal tract & its utilisation in the body.
VITAMIN K2- 7 :-
Responsible for carboxylation of osteocalcin protectins, which reduces the fracture rate.
Plays  a pivotal role in bone metabolism,as well as in the renal reabsorption of calcium.
Lower plasma Vit.k(2-7) levels are associated with increased prevalence, of knee & hand osteoarthritis.
L-METHYLFOLATE:-
Levels have been found to be inversely associated with depressive symptoms & tumour cells.
METHYLCOBALAMIN:-
Is used to trat some nutrition based disease and promotes regeneration to injured nerves.
ZINC & MAGNESIUM:-
Are essential cofactor in bone formation, maintaining bone density, reducing fractures & transportation of calcium - potassium irons.
HIGHLY BENEFICIAL IN:-
Fracture
Ostopenia
Osteomalacia
Post menopausal women
Tetany
Osteoporosis
Low back pain
Hypocalcemia in hypoparathyrodism

Piracetam:-
Improve learning and memory and boost concentration without cousing to -
Play a major role in movement, reasoning, perception and recognition.
Acts on the central nervous system.
Protect the brain against a lack of oxygen.
Protect the cerebral cortex against hypoxia
Inhibits platelet aggregation & reduces blood viscosity
Prescribe in :-
Cortical myoclonus
Stroke
Aphasia & vertigo
As a cognitive enhancer in cerbrocotical insufficiency.

CITICOLINE:-
Acts at multiple levels to support and maintain neural and optimal cognitive function.
Citicoline should be considered as a comprehensive therapeutic agent for supporting brain health.
PIRACETAM:-
Helps reverse the effects of aging on the brain, helps prevent cognitive disorders.
Treats cognitive impairment brought on by alcoholism improves memory.
Paracetam improves the condition of Alzheimer's disease and dementia patients.
Acute ischemic stroke
Senile cognitive impairment
Chronic cerebral vadcular disrase
Head trauma & neuro degenerative disorder
Slow brain aging

OLMESARTAN:-
The only ARB that provides double digit BP reduction
3 dimensional benefits- Efficiency, Protection & Safety
Twice as many patients achive goal BP compared to losartan & valsartan.
HYDROCHLOROTHIAZIDE:-
Decrease excess water & salt in the body, thereby reduces blood pressure.
Prevents strokes, heart attack & kidney problems.
INDICATION:-
Patients whose blood pressure in noy adequately controlled on monotherapy.
Patients with stage-2 hypertension who are at a high risk for cardiovascular events, kidney failure & vision problems.

ACECLOFENAC:-
Excellent analgesic and Anti- inflammatory
Blocks PGE2 secretion at the site of inflammation
Stimulates cartilage matrix synthesis
PARACETAMOL:-
The universally accepted analgesic & antipyretic which acts synergistically with Aceclofenac.
INDICATION:-
Osteoarthritis
Gynaecological pain
Dental pain
Surgical pain
Ent pain

Telsect is safe, effective & better tolerated than ramipril combination.
Telsect tablets are angiotensin 2 receptor blockers (ARB) indicated for treatment of hypertension
Telsect tablet have protective benefits against the vascular and renal damage caused by diabetes & cardiovascular disease (CVD).
INDICATES:-
Hypertension
Early hypertension
Edema in hypertensive
Cardiovascular risk reduction in patients unable to take ACE inhibitors.

METHYLCOBALAMIN:-
Produces neuroprotective & neuropromotive effects.
Provides mecobalamin which increases myelin sheath formation & regenerates neurons.
GABAPENTIN:-
Prevents neuropathic pain & improves neuronal activities.
Reduces the hyper activated neurotransmitter release.
INDICATIONS:-
All peripheral neuropathies
Reflex sympathetic dystrophy
Alcohol induced neuropathy
Post herpetic neuralgia
Diabetic neuropathy
Post surgical neuropathy
Bell's palcy

Better tolerated.
No hepatic or hematological monitoring required.
Linear pharmacokinetics.
Primarily in the treatment of epilepsy and bipolar disorder
Also effective in treating conditions such as varied as mood disorder like anxiety
INDICATION:-
Depression
Sleep disorder
Preventing migraine
Headaches

ACECLOFENAC:- The new age NSAID known for excellent efficacy & safety
SERRATIOPEPTIDASE:- The proteolytic enzyme that exerts benefits in painful inflammatory conditions.
PARACETAMOL:- The universally accepted analgesic, antipyretic.
ELIMINATES BARRIERS:- Dissolves barriesrd of haematoma, pus cells , exudates.
Enhances penetration of drug
Minimises keloid formation
ENHANCES RELIEF:-
Reducess soft tissue swelling.
Improves micro circulation.
Provides potent and better relief.

CEFPODOXIME:-
Useful Alternative to parenteral therapy
Proven superiority over cefixime, co-amoxy clav & cefaclor
OFOXACIN:-
Ofloxacin is a broad- spectrum antibiotic that is active against both gram- positive and gram - negative bacteria.
Excellent efficiency in the treatment of infections (Respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
INDICATIONS :-
Acute bronchitis
Lrti & urti
Pharyngitis & tonsilitis
Typhoid
Gynaecological infections

Regulates cognitive functions.
Enhances cell signalling by increasing the synthesis of neurotransmitters.
Promotes brain metabolism by enhancing acetylcholine production.
Modulates the control of blood flow in the brain.
Safe drug with no serious side effects.
INDICATIONS:-
Neuro Degenerative disorders
Early Alzheimer's, and Parkinson's
Inefficient memory
Marijuana/ Alcohol
Addicts of cocaine
Head trauma & stroke
Cognitive deficits
Amblyopia/ Gloucoma

GLIMEPIRIDE:-
Highly effective sulphonylureas for improved glycemic control.
Devoid of adverse effects on cardiac functions.
METFORMIN:-
An insulin- sensitizing agent, lowering fasting plasma insulin concentrations by inducing greater peripheral uptake of glucose, as well as decreasing hepatic glucose output.
Delays progression to type 2 diabetes in people with impaired glucose tolerance.
VOGLIBOSE:-
An anti- diabetic agent that improves post- prandial hyperglycemia.
Delays the digestion & absorption of sugar, lowering blood sugar levels.
Less gastrointestinal side effects as compared to acarbose reported in some studies.
Provides main benefits by avoiding High level of blood glucose especially after meals.
INDICATION:-
In the management of post prandial hyperglycemia in type-2 diabetics
Diabeties mellitus type 2

CEFPODOXIME:-
Ideal switch over from IV ceftriaxone in serious RTI.
Ensure high efficiency in tough infections
Drug of choice for single dosage of gonococcal urethritis.
CLAVULANIC ACID:-
Extends spectrum of cefpodoxime against beta lactamase strains.
INDICATION:-
Urinary Tract infections
Bronchitis
Gonorrhea
Pneumonia
Typhoid
Skin & soft tissue infaction

Highly selective cox 2 inhibitor.
Superior gastrointestinal tolerability.
Effective in osteoarthritis (OA) pains than diclofenac.
Rapid & durable treatment effects in patients with OA of the knee or hip.
Delivers rapid & powerful relief of excruciating pain with anti inflammatory power similar to indomethacin in acute gouty arthritis.
INDECATION:-
Gout
Spondylitis
Osteoarthritis
Rheumatoid arthritis
Acute low back pain
Post surgical pain management

THIOCOLCHICOSIDE:-
Class of drug other agents used as centrally acting muscle relaxants.
More effective in backache, Neuralgia pain, parkinsonism, sciatic pain.
Found to displace both (3H) gamma butyric acid and (3H) strychnine binding.
Effective anit inflammatory & analgesic properties as well as pronounced convulsant activity.
ETORICOXIB:-
Effective for the symptomatic treatment of osteoarthritis, rheumaloid arthritis, ankylosing spondylitis and acute gouty arthritis.
More effective as compared to naproxen for treating patients with RA.
USE IN:-
Rheumatoid arthritis
Acute gouty arthritis
Chronic musculoskeletal pain
Post-operative pain
Osteoarthritis

Paracetamol produces analgesia by elevation of the pain threshold and antipyretics effect through action on the hypothalamic heat-regulating center.
Phenylephrine as sympathomimetic decongestant reduces the nasal congestion due to increased nasal blood flow associated with clods and influenza.
Caffeine is a xanthine alkaloid & a stimulant drug shows effects within 15 min.
Diphenhydramine is an antihistamine used in the treatment of allergies & relive cold & cough caused by minor throat or airway irritation.
Seasonal allergic rhinitis
Upper respiratory allergies
Sinus/ Nasal congestion
Cold, allergies & hay fever