Sitagliptin Phosphate and Metformin HCl Tablet is a combination medication used to treat adults with Type 2 diabetes mellitus. It is prescribed when diet and exercise alone, or a single anti-diabetic medication, are not enough to effectively control blood sugar levels. This tablet combines two different drugs with complementary mechanisms of action to provide better glycemic control.
Sitagliptin Phosphate: This is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of "incretin" hormones in the body. These hormones are released after a meal and stimulate the pancreas to produce more insulin when blood sugar levels are high. Sitagliptin also reduces the amount of glucose produced by the liver.
Metformin HCl: This is a biguanide that works primarily by decreasing glucose production in the liver. It also helps the body's cells become more sensitive to insulin, allowing them to use glucose more effectively.
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