AYUGANC Ganciclovir For Injection BP, 500 mg/vial

Product Name

Ganciclovir for Injection BP

Product Description

Ganciclovir for Injection BP is a potent antiviral agent used for the treatment and prevention of cytomegalovirus (CMV) infections in immunocompromised patients, including organ transplant recipients and HIV-infected patients. It is a synthetic nucleoside analog that inhibits viral DNA polymerase, thereby preventing viral replication.

This sterile injectable formulation is intended for intravenous administration under specialist supervision, ensuring rapid therapeutic action against CMV infections.

Composition

Each vial contains:

• Ganciclovir BP – 500 mg / 250 mg

• Excipients: q.s. sterile water for injection (lyophilized powder)

After reconstitution, it is ready for intravenous infusion.

Major Indications / Uses Primary Indications

• Treatment of CMV retinitis in immunocompromised patients (e.g., HIV/AIDS)

• Prevention of CMV disease in organ transplant recipients (kidney, liver, heart)

• Treatment of severe systemic CMV infections in immunocompromised patients

Other Uses

• Adjunct therapy in CMV prophylaxis for high-risk patients

• Management of CMV pneumonia, gastrointestinal, or hepatic involvement

Dosage & Administration

• Route: Intravenous (IV) infusion

• Adult Dose: Typically 5 mg/kg IV every 12 hours for 14–21 days for induction therapy

• Maintenance Dose: 5 mg/kg IV once daily, adjusted for renal function

• Pediatric Dose: Weight-based, adjusted per protocol

• Monitoring: Renal function, complete blood count, liver function, and electrolyte levels

⚠ Administer only under specialist supervision

Packaging Details

• Available strengths: 250 mg, 500 mg vials

• Lyophilized powder for injection

• Hospital and bulk packaging available

Storage Conditions

• Store 2–8°C (Refrigerated)

• Protect from light and moisture

• Do not freeze

• Keep out of reach of children