Ceftazidime 1 gm Injection Cefwide, 1000 mg

Specification for Ceftazidime 1 gm Injection Cefwide

General Information

• Brand Name: Cefwide
• Generic Name: Ceftazidime
• Dosage Form: Injection
• Strength: 1 gm
• Manufacturer: Neon Laboratories Ltd.
• Country of Origin: India

Composition

• Active Ingredient: Ceftazidime pentahydrate equivalent to 1 gm of Ceftazidime
• Inactive Ingredients: None

Pharmaceutical Specifications

• Appearance: White to off-white crystalline powder
• Solubility: Freely soluble in water
• pH: 4.5-6.5
• Osmolality: 290-350 mOsmol/kg
• Sterile: Meets USP sterility requirements
• Endotoxin:<0.25 EU/mg
• Potency: 90-110% of the labeled amount

Indications

• Treatment of serious bacterial infections caused by susceptible organisms, including:
  • Urinary tract infections
  • Respiratory tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Intra-abdominal infections
  • Septicemia
  • Meningitis
  • Surgical prophylaxis

Dosage and Administration

• Adults: 1-6 gm daily in divided doses
• Children: 30-100 mg/kg daily in divided doses
• Route of Administration: Intravenous or intramuscular injection

Contraindications

• Hypersensitivity to Ceftazidime or other cephalosporins

Warnings and Precautions

• Use with caution in patients with renal impairment
• May cause allergic reactions, including anaphylaxis
• May cause Clostridium difficile-associated diarrhea
• Prolonged use may lead to superinfection

Adverse Reactions

• Common: Injection site reactions, diarrhea, nausea, vomiting, rash
• Uncommon: Headache, dizziness, eosinophilia, neutropenia, thrombocytopenia
• Rare: Seizures, Stevens-Johnson syndrome, toxic epidermal necrolysis

Drug Interactions

• May interact with probenecid, aminoglycosides, loop diuretics, and anticoagulants

Storage and Handling

• Store at 2-8°C (36-46°F)
• Protect from light
• Use within 24 hours after reconstitution

Disposal

• Dispose of unused medication properly

Additional Information

• Consult a healthcare professional for complete information on Cefwide

Note: This specification is intended for informational purposes only and should not be used as a substitute for professional medical advice.