CEFTILEX-SB 4500 is a brand name for a veterinary injectable antibiotic combination containing Ceftriaxone and Sulbactam in a total strength of 4.5 grams (4500 mg).
This medication is typically formulated as a dry powder for injection that is reconstituted with sterile water before administration.
Composition
The common composition for a 4.5 g (4500 mg) preparation of this type is:
Ceftriaxone (a third-generation cephalosporin antibiotic): 3.0 grams (3000 mg)
Sulbactam (a beta-lactamase inhibitor): 1.5 grams (1500 mg)
The total active drug content is 4500 mg (4.5 g).
Mechanism of Action
Ceftriaxone is a broad-spectrum antibiotic that works by inhibiting the synthesis of the bacterial cell wall, which is essential for bacterial survival, leading to the death of the bacteria (bactericidal action).
Sulbactam is a beta-lactamase inhibitor. Many bacteria produce enzymes called beta-lactamases that can inactivate Ceftriaxone. Sulbactam prevents this inactivation, thereby protecting the Ceftriaxone and enhancing its effectiveness against resistant bacteria.
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