Cefuroxime has bactericidal activity against a wide range of common pathogens, including beta-lactamase producing strains. The bactericidal action of cefuroxime results from inhibition of cell wall synthesis by binding to essential target proteins. Cefuroxime has good stability to bacterial beta-lactamases.
Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus. Clavulanic acid binds to and inactivates them thus preventing the destruction of cefuroxime that is a substrate for this enzyme. It has poor intrinsic antimicrobial activity, but it is an irreversible binder of ß-lactamases produced by a wide range of gram positive and gram negative microorganism.
Rationale for combination:
Although Clavulanic acid does have some degree of bacterial activity, its principal role is as a beta-lactamase inhibitor. Beta-lactam antibiotics, such as the penicillins and cephalosporins, act by disrupting the development of bacterial cells walls thus causing the disintegration of the bacteria. However, some bacteria acquire the genes to produce enzymes which inactivate this mode of action - so called beta-lactamases - drastically reducing the efficacy of this class of antibiotics.
Find products similar to Cefuroxime And Potassium Clavulanate Tablets, 500mg
Established in the year at 2011, we "Astemax Biotech Private Limited", are one of the renowned manufacturer, wholesalers, traders exporterof an extended collection of Pharmaceutical Products and We are offering a complete general range of Pharmaceutical Medicine, Pharmaceutical Injections, and Pharmaceutical Tablets. Offered products are prepared using only quality tested ingredients at our well-equipped infrastructure unit. These products are admired for their high purity, accurate preparation, non-toxicity. The state-of-art infrastructure owned by us forms the backbone of our organization as it assists in efficient analyzing of the production capacity. We have installed some of the best technologies and advanced machinery in all our units, which helps in maintaining the high rate of production with utmost ease. We have a team of professionals, who have experience in this domain. Their knowledge had led us to mark a good name in this competitive market. Working under the specification laid by the industry has drafted the way for us to reach the pinnacle of success. These products are available in various packining option and customised mrp price as per the variegated need of the customers, these products are who-gmp certified and trade mark registered, all products are patent by astemax, higlight mark at rx for etchical operation in market. our highly satisfied clients are one of the beggest reason of our success in pharma industry, the experience and expertise they bring in has inspired us to spread our wings accross the nation and keep persisting to achieve the top position in market, our association with reputed C & F agents is also one of the vital factors in assuring a timely delivery to our client, thus; we have created a huge benchmark with our ability to offer a qualitive range timely and efficient manner.
To formulate the pharmaceutical products for our customers, our vendors are supported by well-equipped infrastructure. Together with this, the offered products are available in various packaging options in order to meet the exact requirements of clients. Also, we endeavor to become a famous firm with the help of our qualified team of professionals and advanced research and technology. Our customized packaging options and affordable rates also help us in attaining high patron satisfaction.
Our managing director 'Mr. Rahul Chaudhary' is instrumental in our success in this domain. His in-depth and sharp knowledge have enabled us to garner a huge clientele
