Geomax Soft Gel Capsule

ABSORPTION

Vitamin B1 -Absorbed mainly from duodenum, by both active and passive processes. Vitamin B5 - When found in foods, most pantothenic acid is in the form of CoA or acyl carrier protein (ACP). For the intestinal cells to absorb this vitamin, it must be converted into free pantothenic acid. Within the lumen of the intestine, CoA and ACP are hydrolyzed into 4'-phosphopantetheine. The 4'-phosphopantetheine is then dephosphorylated into pantetheine. Pantetheinase, an intestinal enzyme, then hydrolyzes pantetheine into free pantothenic acid. Free pantothenic acid is absorbed into intestinal cells via a saturable, sodium-dependent active transport system. At high levels of intake, when this mechanism is saturated, some pantothenic acid may also be absorbed via passive diffusion. As intake increases 10-fold, however, absorption rate decreases to 10%. Vitamin B2-Vitamin B2 is readily absorbed from the upper gastrointestinal tract. Vitamin B6 -The B vitamins are readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Pyridoxine is absorbed mainly in the jejunum. Vitamin-A-Readily absorbed from the normal gastrointestinal tract. Vitamin B12-Readily absorbed in the lower half of the ileum. Vitamin E-50 to 80% absorbed from gastrointestinal tract. Iron -The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.