Griseofulvin (250mg) Griseofulvin FP

Griseofulvin 250mg Tablets are an antifungal medication primarily used to treat fungal infections of the skin, hair, and nails caused by dermatophytes. It works by inhibiting fungal cell division, leading to the eventual elimination of the infection.

1. Fungal Infections:
   • Tinea corporis: Ringworm of the body.
   • Tinea cruris: Ringworm of the groin (jock itch).
   • Tinea pedis: Ringworm of the feet (athlete's foot).
   • Tinea capitis: Fungal infections of the scalp and hair.
   • Onychomycosis: Fungal infections of the nails.
2. Chronic or Severe Fungal Infections:
   • Especially in cases where topical treatments are ineffective or inappropriate.

• Mechanism of Action:
  • Griseofulvin binds to keratin in newly forming skin, hair, and nails, making them resistant to fungal invasion.
  • It disrupts fungal cell division by interfering with the mitotic spindle, leading to the fungus's death.

1. Dosage:

   • The typical dose depends on the severity and location of the infection:
     • Adults: 500mg to 1000mg per day, often divided into two doses.
     • Children: Dosage is based on weight and determined by a doctor.
   • Follow your healthcare provider's prescription for exact dosing.

2. Administration:

   • Take the tablet with a fatty meal (e.g., milk or butter) to enhance absorption.
   • Swallow the tablet whole with water.

3. Duration:

   • Treatment duration varies based on the site of infection:
     • Skin: 2-4 weeks
     • Scalp: 4-6 weeks
     • Nails: Up to 6 months or longer

• Effectively treats persistent or severe fungal infections.
• Reduces symptoms like itching, redness, and scaling.
• Prevents the spread of infection to other areas of the body or to others.

1. Common Side Effects:

   • Nausea or vomiting
   • Diarrhea or stomach discomfort
   • Headache
   • Fatigue or dizziness

2. Less Common Side Effects:

   • Skin rash or itching
   • Sensitivity to sunlight (photosensitivity)
   • Oral thrush or secondary infections (due to long-term use)

3. Rare but Serious Side Effects:

   • Liver issues (e.g., jaundice, elevated liver enzymes)
   • Severe allergic reactions (e.g., swelling, difficulty breathing)
   • Neurological symptoms (e.g., confusion, tingling sensations)

1. Medical History:

   • Inform your doctor if you have liver disease, lupus, or a history of allergic reactions to antifungal medications.

2. Pregnancy and Breastfeeding:

   • Not recommended for use during pregnancy due to potential harm to the fetus. Use effective contraception during treatment and for at least 1 month after stopping the medication.
   • Avoid during breastfeeding unless advised by a doctor.

3. Sun Protection:

   • Use sunscreen and protective clothing to avoid photosensitivity reactions.

4. Alcohol Consumption:

   • Avoid alcohol while taking Griseofulvin as it may increase the risk of side effects like flushing, rapid heartbeat, or nausea.