Chemical Constituents and Components :Main chemical components are tinocordifolin, tinocordifolioside, tinosponone, tinocordioside, cordioside, picroretine, colombine, and columbin.
1. It stimulates the function of macrophage and neutrophilla to produce leucocytosis.
2. It inhibits lipid peroxidation and free radical formation.
3. It decreases the capillary permeability and reduces the number of disrupted mast cells.
4. It exhibited insulin like action and significantly reduces the blood sugar level.
5. It possesses antineoplastic activity and shows the cytotoxic effect on tumor cells by reducing GSH (glutathione) concentration. Bitters: 1. It reduced oxidative stress and lowers the blood sugar level in the body. 2. It enhanced lipid peroxidation in the liver and blood of tumor-bearing models and accompanied by significant decreases in the activities of GSH-dependent antioxidant. 3. It lowers the lipid levels especially cholesterol and LDL-cholesterol in the body.
Curing Diseases: 1. It is used in burning sensation, hyperdipsia, intermittent and chronic fevers.
2. It is used in inflammations, gout and skin diseases.
3. It is useful in flatulence, dyspepsia, vomiting and stomach problems.
4. It is used in leprosy, diabetes, cardiac debility, jaundice, and general weakness.
5. It is also used in anemia, uropathy, and splenopathy.
Research Information: Tinospora cordifolia shows significant bactericidal activities. It improves bacterial clearance as well as improves phagocytic and intracellular bactericidal capacities of neutrophils. It also stimulates macrophage action. As a result, it stimulates the immune system of the body. (Ref. Thatte UM, Kulkarni MR and Dahanukar SA, Immunotherapeutic modification of Escherichia coli peritonitis and bacteremia by Tinospora cordifolia, IPGM (1992) 38 (1): 13-15)
Possible Combinations :Tinospora cordifolia + commiphora mukul + rubia cordifolia + emblica officinalis + moringa pterygosperma + glycyrrhiza glabra (enhance immunity)