Each 5 ml contains:
|Levocetirizine Dihydrochloride||I.P.||5 mg|
|Ambroxol hydrochloride||I.P.||30 mg|
|In a flavoured mentholated syrupy base|| || |
|Colour: Tartrazine and brilliant blue FCF|| || |
: Ambroxol is the metabolite of bromhexine and a mucolytic agent. Ambroxol acts as secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Levocetirizine dihydrochloride is the R enantiomer of cetirizine hydrochloride, a racemic compound with antihistaminic properties.
MECHANISM OF ACTION
: Ambroxol facilitates mucociliary clearance by intensifying the motion of the cilia present on the ciliated respiratory epithelium. Levocetirizine, the active enantiomer of cetirizine, is an antihistamine; its principal effects are mediated via selective inhibition of H1 receptors. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs.6 nmol/L, respectively). INDICATIONS
: Indicated for the treatment of whooping cough, post-surgical cough, dry cough, smokers cough, chronic cough.
: Hypersensitivity to any of the ingredients of product.
: As directed by the physician. STORAGE
: Store in cool and dry place. Recap the bottle tightly after use.
SHAKE WELL BEFORE USE