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Antibiotics & Anti-Infectives
Azithromycin Injection
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| Composition : | 100mg, 200 mg |
| Indications : | Pharyngitis, tonsillitis, sinusitis, otitis media, pneumonias, acute exacerbations of chronic bronchitis, staphylococcal and streptococcal skin and soft tissue infections, chlamydial pulmonary and genital infections and gonorrhoea. Prophylaxis and treatment of MAC infection in AIDS patients. Other uses like typhoid, toxoplasmosis and malaria are being explored. |
| Safety Profile : | It is comparatively newer , should be used carefully with non-antihistaminics. |
| Adverse Effects : | Mild gastric upset, abdominal pain, headache, dizziness etc. |
| Drug Interactions : | No interaction with hepatic cytochrome P450 enzyme |
| Dosage : | 500mg OD orally, URTI/LRTI, skin & soft tissue infections: 500mg OD followed by 250mg OD Children :10mg/kg/day for 3 days |
| Purity : | Not less than 99%. |
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Injection
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Each vial contains:-
Meropenam - 500 mg and 1 gm
Quality Specification:
Chromatographic Purity - NLT 99.5%%
Pack Size: vial
| Composition : | 125mg, 250mg,500mg,1gm |
| MEROPENAM :- | It is a synthetic Carbapenem Beta - Lactum . It has a potent bactericidal action against a broad spectrum of aerobic and anerobic bacteria. |
| Indication : | Pneumonias, gynecological infections, skin and soft structure infections, meningitis, septicaemia and adult febrile neutropenia. |
| Dosage and administrations :- | Administered as an intravenous injection over approkximately 5 minutes or by intravenous infusion over approximately 15-30 minutes with compatible infusion (50-200ml) fluid. |
| Adult :- | Pneumonias, UTI, skin and skin structure infections :500mg 8hourly. Nosocomial Pneumonias, peritonitis, septicemia: 1g every 8hours. Meningitis : 2g every 8 hours |
| Contra-Indications :- | Hypersensitivity to ingredients. Hypersensitivity to pencilins or other beta-lactam . |
| Warning : | |
| Special Precautions :- | |
| Paediatrics :- | Safety is not established in patient with neutropenia or primary/secondary immuno deficiency. Safety is not established in infants under 3 months of age. |
| Pregnancy :- | Safety is not established |
| Lactation :- | Safety is not established. |
| Elderly :- | Safe for elderly with normal renal functions. |
| Side–effects :- | Serious adverse effects are rare. Local IV injection site reaction, site reaction and neutrophilia. Headache, paresthesia, convulsions, oral and vaginal candidiasis. |
| Drug Interactions :- | Nephrotoxic drugs, probenocid etc. |
| Purity : | Not less than 99%. |
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