Varuna Export And Imports

Anticancer medicines, also known as chemotherapy drugs or antineoplastic agents, are medications used to treat malignant tumors and cancers. They work by targeting rapidly dividing cancer cells, either killing them (cytotoxic) or inhibiting their growth (cytostatic), while sparing normal cells as much as possible.

Ibrutinib 140 mg is an oral targeted cancer therapy medication belonging to the class of Bruton tyrosine kinase (BTK) inhibitors. Each hard gelatin capsule contains 140 mg of ibrutinib as the active ingredient.

Ibrutinib blocks the activity of Bruton tyrosine kinase (BTK), a key enzyme in the signaling pathway that helps B‑cells (a type of white blood cell) survive and proliferate. By inhibiting BTK, ibrutinib helps slow or stop the growth of malignant B‑cells in certain blood cancers.

Doxorubicin is a chemotherapy medication classified as an anthracycline antibiotic. It is used to treat a variety of cancers by interfering with the growth and spread of cancer cells. The “IP” indicates that the formulation meets Indian Pharmacopoeia standards.

Cytrabin 1000 mg Injection BP contains Cytarabine (Ara-C), an antineoplastic (chemotherapy) agent used primarily in the treatment of hematological malignancies. It works by interfering with DNA synthesis, leading to apoptosis of rapidly dividing cancer cells.

• Generic Name: Cytarabine (Ara-C)

• Brand Name: Cytrabin

• Strength: 1000 mg

• Dosage Form: Injection

• Route of Administration: Intravenous (IV), Intrathecal (specialist use)

• Pharmacopoeia Standard: BP (British Pharmacopoeia)

• Therapeutic Class: Antineoplastic / Chemotherapy agent

• Appearance: The capsule is often a multi-coloured shell (e.g., red and yellow) containing the active drug as a yellowish powder.
• Packaging: It is commonly sold in bottles of 30 capsules or blister packs, depending on the manufacturer (such as Eisai Inc. for the brand Lenvima, or generic versions like Lenvat or Lenvenib).

Busulfan 2 mg Tablet is a prescription anti-cancer (chemotherapy) medication belonging to the class of drugs known as alkylating agents. It is primarily used to treat certain blood disorders and cancers.

Fludarabine 50 mg Injection is a chemotherapy medicine in the class of purine analogues (antimetabolites) used mainly for treating certain blood cancers, particularly chronic lymphocytic leukemia (CLL). It works by interfering with DNA synthesis in cancer cells, slowing their growth and leading to cell death.

This medication is supplied as a sterile powder for solution for injection or infusion and must be administered intravenously (IV) by a trained healthcare professional. It’s not suitable for patient self‑administration. 

Afatinib 40 mg is an oral targeted therapy medication classified as a tyrosine kinase inhibitor (TKI). It works by irreversibly blocking EGFR (epidermal growth factor receptor) and HER2 signaling pathways, which are often overactive in certain cancers, especially non-small cell lung cancer (NSCLC). By inhibiting these pathways, afatinib slows or stops the growth of cancer cells.

Afatinib binds covalently to the tyrosine kinase domains of EGFR and HER2, blocking their autophosphorylation. This inhibits downstream signaling that promotes cell proliferation, survival, and tumor progression.

Dacarbazine 500 mg Injection is a cytotoxic chemotherapy medication supplied as a sterile lyophilized powder for intravenous administration after reconstitution. Each vial contains Dacarbazine equivalent to 500 mg of active drug.

Mechanism of Action:
Dacarbazine is an alkylating agent that works by interfering with DNA synthesis in rapidly dividing cancer cells, leading to cell death. It is classified as a triazene derivative and is used in oncology for its anti-tumor activity.

Indications:

• Malignant melanoma

• Hodgkin’s lymphoma (as part of combination chemotherapy regimens such as ABVD: Adriamycin, Bleomycin, Vinblastine, Dacarbazine)

• Other solid tumors or lymphomas as determined by an oncologist

Formulation:

• Lyophilized powder in sterile vials

• Reconstituted with appropriate diluents and administered intravenously under medical supervision

Important Notes:

• Administered only by trained healthcare professionals in a hospital/clinic setting.

• Requires monitoring for hematologic toxicity, liver function, nausea, and vomiting.

• Dosage is based on body surface area (BSA) and treatment protocol.

Olaparib 150 mg is an oral targeted therapy tablet belonging to the class of PARP (Poly ADP-Ribose Polymerase) inhibitors. Each tablet contains 150 mg of olaparib as the active ingredient.

Olaparib inhibits PARP enzymes, which are critical for repairing DNA damage in cells. Cancer cells with BRCA1 or BRCA2 mutations rely heavily on PARP for DNA repair. By blocking PARP, olaparib causes DNA damage to accumulate in these cells, leading to cancer cell death, while sparing most normal cells.

Palbociclib 125 mg is an oral targeted cancer medicine belonging to the class of cyclin‑dependent kinase (CDK) 4/6 inhibitors. Each hard gelatin capsule contains 125 mg of palbociclib as the active ingredient.

How It Works:
Palbociclib works by inhibiting CDK4 and CDK6, which are enzymes involved in cell division. By blocking these enzymes, it slows down or stops the growth of cancer cells, especially in hormone‑dependent breast cancers.

Vinorelbine 10 mg Injection IP is an anti-cancer (chemotherapy) medicine used in the treatment of various types of cancers. It belongs to the vinca alkaloid group of medicines and works by inhibiting cancer cell division, thereby slowing or stopping tumor growth.

It is administered intravenously and must be given under the supervision of a qualified healthcare professional.

Paclitaxel belongs to the taxane class of antineoplastic agents. It works by inhibiting cancer cell division through stabilization of microtubules, which prevents normal breakdown during cell division and leads to cell death. The 300 mg injection is supplied as a concentrated solution for intravenous infusion and is always administered under specialist supervision.

Uses / Indications:

• Ovarian cancer

• Breast cancer

• Non-small cell lung cancer

• Kaposi’s sarcoma (AIDS-related)

• Generic Name: Bortezomib

• Strength: 3.5 mg

• Dosage Form: Injection

• Form: Lyophilized powder for reconstitution

• Route of Administration:

  • Intravenous (IV)

  • Subcutaneous (SC)

• Packaging Type: Single-dose vial

• Prescription: Prescription medicine only

Methotrexate 500 mg Injection IP is a prescription anticancer and immunosuppressive medicine belonging to the antimetabolite class. It is widely used in oncology and autoimmune therapy to slow or stop the growth of rapidly dividing cells.

This injection works by inhibiting dihydrofolate reductase, an enzyme essential for DNA synthesis and cell replication. By blocking this process, Methotrexate interferes with the multiplication of cancer cells and abnormal immune cells, helping control disease progression.

Methotrexate 500 mg Injection IP is commonly prescribed for the treatment of leukemia, lymphoma, breast cancer, osteosarcoma, and other solid tumors. It is also used in severe psoriasis and rheumatoid arthritis under specialist supervision. The injection is administered intravenously, intramuscularly, or intrathecally, strictly as directed by a qualified healthcare professional.

Due to its potent action, treatment requires careful dosing and regular monitoring of blood counts, liver function, and kidney function. This product complies with Indian Pharmacopoeia (IP) standards and is supplied in sterile glass vials for hospital and clinical use.