A topical analgesic that treats aches and pains of the muscles/joints associated with backache, arthritis, strains, sprains, and bruises. Reduces inflammation by inhibition of the COX isoenzymes and thereby decreasing the synthesis of prostaglandin. (Bindu Nair, 2010) A safe and effective in treating a variety of painful conditions, including musculoskeletal pain and sports injuries. (J. V. Pergolizzi Jr MD, 2018) The first-line therapy for acute and chronic pain and inflammation from a variety of causes. Provides significant relief from the pain associated with mild to moderate muscle strain. (Yoshinobu Higashi, 2010) An efficacious drug for the treatment of acute pain in chronic arthritic and rheumatic pain. (Lorna Mason, 2004) Significantly reduces pain, morning stiffness and improves physical function in patients with osteoarthritis of the knee. (Banning, 2008) Provides significant pain relief in patients with sports and soft tissue injuries involving the ankle, knee or shoulder. (Banning, 2008)

An anticonvulsant that is used extensively in adults with indications for epilepsy, acute mania related to bipolar disorder and migraine prophylaxis. (Manasi Rana, 2005) Has a broad spectrum of activity in the treatment of bipolar depression and rapid cycling, psychotic symptoms, impulsive aggression, and post-traumatic stress disorder. (Lori L Davis, 2004) An efficacious candidate in the treatment of bipolar disorder depression. (David J Bond, 2010) Has a significant potential to improve patient compliance with bipolar disorder. (Lori L Davis, 2004) An effective and well-tolerated prophylactic treatment option for migraine and cluster headaches. (R Michael Gallagher, 2002) An efficacious, well-tolerated, safe, and easy-to-use prophylactic antimigraine medication. (Frederick G Freitag, 2002)

A non-steroidal anti-inflammatory drug that minimizes inflammation and alleviates pain in arthritic and painful conditions. Eases pain and inflammation by blocking pain-causing enzymes cyclo-oxygenase-2. An alternative to other selective and traditional NSAIDs in treating patients with arthritis and other painful conditions. (Kubler, 2006) Demonstrates significantly greater benefit than diclofenac. (Kubler P. B., 2006) Provides a similar efficacy compared to the traditional NSAIDs (including naproxen, diclofenac, and ibuprofen) in pain, osteoarthritis, and rheumatic arthritis. (KUMARAVELU P, 2010) Produces good quality pain relief after acute postoperative pain in adults. (Devalina Goswami c. a., 2020) A safe, well-tolerated, and efficacious drug for the treatment of ankylosing spondylitis than naproxen. (Désirée van der Heijde 1, 2005) More effective than naproxen 500 mg for treating patients with rheumatoid arthritis over 12 weeks. (Alan K Matsumoto, 2002) Provides similar symptomatic relief to celecoxib in patients with osteoarthritis. (Katherine F Croom, 2009)

An analgesic drug that relieves musculoskeletal pain in conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Possesses analgesic, anti-inflammatory, anti-edematous and antioxidant properties. (Khobre, 2017) Inhibits inflammatory manifestations in arthritis and other inflammatory diseases. (Tina Kauss, 2008) Produces certain analgesic and anti-inflammatory effects in patients with rheumatoid arthritis. (Rajendra Pavan, 2012) Offers superior analgesia as compared to Ibuprofen in surgical tooth extraction patients. (Dr Lovisha Jhunjhun Wala, 2020) Eases arthritis symptoms, including joint pain, stiffness, and improves pain after mandibular third molar surgery. (Arka Jyoti Chakraborty, 2021) A safe and effective option for the management of joint pain. Shows significant improvement in functionality in patients with osteoarthritis. An effective alternative to NSAIDs in reducing the postoperative pain associated with surgical extraction of third molars.(Dr Lovisha Jhunjhun Wala, 2020)

A potent dual-action agent that contains a painkiller as well as a muscle relaxant. (Disha Palte, 2015) Reduces mild to moderate pain and inflammation at the injured site. A beneficial drug that lessens the pain intensity and ameliorates the functional ability. Significantly reduces the pain intensity and alleviates mobility in patients with acute lower backache-associated muscle spasms. Provides a significantly better improvement in inflammation than each of the treatments alone. (Disha Palte, 2015) Relieves the stiffness of muscle and improves the movements of the muscle. A promising therapeutic candidate for orthopedic, traumatological, rheumatologic disorders, and muscular spasms. (Disha Palte, 2015)

An anti-inflammatory and spasmolytic drug relieves mild to moderate pain in the muscles associated with spasms. Alleviates gastrointestinal and genitourinary smooth muscle spasms. A highly potent spasmolytic agent with excellent smooth muscle relaxant properties. (S. A. Shah, 2011) Inhibits the release of certain chemical messengers that cause abdominal pain and inflammation. An effective candidate that eases spasmodic pain arising from smooth muscle diseases like irritable bowel syndrome, and intestinal, biliary, or ureteric colic. (Nijhawan, 2021) Possesses a good relaxing effect on intestinal smooth muscle, which assists in alleviating pain. (Ramesh R. Rai, 2014) A suitable, effective, and well-tolerated treatment option for primary dysmenorrhea. (Anil Pareek, 2010) Shows superior anti-inflammatory properties and an improved safety profile than conventional NSAIDs. (Vinod K M, 2013) A promising approach ameliorates post-operative pain associated with spasms and inflammation. (Vinod K M, 2013) Significantly more effective than aceclofenac alone in relieving postoperative pain following laparoscopic surgeries. (Vinod K M, 2013)

Belongs to a group of medicines called analgesics and antipyretics that relieves mild to moderate pain and feverishness in children from six years onward. An appropriate therapeutic drug for infants and children for pain relief and as an antipyretic. (Kanakkande Aabideen, 2011) Provides fast and effective relief from headaches, toothaches, backaches, and musculoskeletal pain associated with/without fever. Reduces the intensity of pain signals to the brain and prevents the release of substances that increases pain and body temperature. Achieves effective antipyresis and provides a symptomatic improvement in children with febrile illness. An effective analgesic that is useful in a broad range of clinical conditions. The first-choice over-the-counter treatment for analgesia and antipyresis in children. (N Cranswick, 2000)

A potent dual-action agent that contains a painkiller as well as a muscle relaxant. (Disha Palte, 2015) Reduces mild to moderate pain and inflammation at the injured site. A beneficial drug that lessens the pain intensity and ameliorates the functional ability. Significantly reduces the pain intensity and alleviates mobility in patients with acute lower backache-associated muscle spasms. Provides a significantly better improvement in inflammation than each of the treatments alone. (Disha Palte, 2015) Relieves the stiffness of muscle and improves the movements of the muscle. A promising therapeutic candidate for orthopedic, traumatological, rheumatologic disorders, and muscular spasms. (Disha Palte, 2015)

It belongs to a group of medicines called analgesics and antipyretics that relieves mild to moderate pain and feverishness in children from six years onward. An appropriate therapeutic drug for infants and children for pain relief and as an antipyretic. (Kanakkande Aabideen, 2011) Provides fast and effective relief from headaches, toothaches, backaches, and musculoskeletal pain associated with/without fever. Reduces the intensity of pain signals to the brain and prevents the release of substances that increases pain and body temperature. Achieves effective antipyresis and provides a symptomatic improvement in children with febrile illness. An effective analgesic that is useful in a broad range of clinical conditions. The first-choice over-the-counter treatment for analgesia and antipyresis in children. (N Cranswick, 2000)

A nonsteroidal anti-inflammatory drug is used to relieve pain and inflammation. Possesses analgesic, antipyretic and anti-inflammatory properties. (Chiara Leuratti, 2019) Blocks the release of certain chemical messengers that cause pain and inflammation. Effectively treats acute moderate to severe forms of pain. (Chiara Leuratti L. L., 2019) The most effective inhibitor of the production of prostaglandin. (Alfaro) Offers rapid and sustained pain relief for patients who do not achieve pain resolution with other medications. A safe and effective medication for the treatment of rheumatic diseases. (Khan, 1987) The first choice for the treatment of acute and chronic painful and inflammatory conditions. (P A Todd, 1988) Relieves moderate to severe postoperative pain in patients undergoing dental surgery or minor orthopedic surgery. (Hannah A Blair, 2015) Considered an opioid-sparing agent for postoperative analgesia. (Ranju Singh, 2011) A suitable alternative for pain management in chronic kidney disease patients. (Sharad Sheth, 2021) As effective as indomethacin or sulindac in treating ankylosing spondylitis. (Small, 1989) Exerts substantially greater potency against cyclo-oxygenase-2 than indomethacin and naproxen. (Dr. Ajay Kumar Shukla, 2015) Provides effective and better analgesia in acute postoperative pain than tramadol. (Dr. Ajay Kumar Shukla, 2015)

An analgesic is prescribed for the treatment of osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. An effective non-steroidal agent that possesses potent anti-inflammatory and analgesic activities. (S Lynch, 1986) Significantly reduces the intensity of pain and improves the mobility of patients with low back pain. A potent cyclooxygenase inhibitor that suppresses the biosynthesis of prostaglandins which are important in pain and inflammatory pathways. (Bethesda (MD), 2012) Treats various musculoskeletal conditions, including osteoarthritis of all joints. (Nihat Akbulut, 2013) Effectively treats pain, inflammation caused by arthritis, and pain resulting from minor surgery. (S Lynch, 1986) A preferred option for lower back pain with muscle spasms. (Darius F Soonawalla, 2008) Provides sustained symptom relief over tizanidine in patients with accompanying muscle spasms. (Darius F Soonawalla, 2008) A well-tolerated alternative to other NSAIDs in the treatment of arthritic diseases and pain from various origins. (J A Balfour, 1991)

A non-steroidal anti-inflammatory drug that minimizes inflammation and alleviates pain in arthritic and painful conditions. Eases pain and inflammation by blocking pain-causing enzymes cyclo-oxygenase-2. An alternative to other selective and traditional NSAIDs in treating patients with arthritis and other painful conditions. (Kubler, 2006) Demonstrates significantly greater benefit than diclofenac. (Kubler P. B., 2006) Provides a similar efficacy compared to the traditional NSAIDs (including naproxen, diclofenac, and ibuprofen) in pain, osteoarthritis, and rheumatic arthritis. (KUMARAVELU P, 2010) Produces good quality pain relief after acute postoperative pain in adults. (Devalina Goswami c. a., 2020) A safe, well-tolerated, and efficacious drug for the treatment of ankylosing spondylitis than naproxen. (Désirée van der Heijde 1, 2005) More effective than naproxen 500 mg for treating patients with rheumatoid arthritis over 12 weeks. (Alan K Matsumoto, 2002) Provides similar symptomatic relief to celecoxib in patients with osteoarthritis. (Katherine F Croom, 2009)

A new generation antihistamine has been widely used in allergic diseases. (Cheng-zhi Huang, 2019) A promising therapeutic option for treating allergy-mediated respiratory and dermatologic diseases. (Suzanne G Meeves, 2003) A safe and effective drug in the treatment of autumnal seasonal allergic rhinitis and chronic idiopathic urticarial. (T B Casale, 1999) Has a better safety profile as compared to second-generation antihistamines. (Cheng-zhi Huang, 2019) Significantly more effective than loratadine in relieving itchy, watery, red eyes symptoms and nasal congestion of seasonal allergic rhinitis patients. (P Van Cauwenberge, 2000) Effective in lessening the symptoms of chronic idiopathic urticaria. (K Simpson, 2000) Produces greater improvements in quality of life than loratadine to an extent. (K Simpson, 2000)

A dual-action drug (non-opioid analgesic) and (analgesic and antipyretic) that relieves pain and inflammation. Works by the release of certain chemical messengers that cause fever, pain, and inflammation. A pain reliever that treats pain associated with muscles, joints, dysmenorrhea, headache, cancer, and pain after surgery. A well-known centrally-acting non-opioid analgesic and muscle relaxant agent. (Devulder, 2010) Exerts a significant reduction in pain intensity in chronic headaches. (S Harish, 2012) Offers an alternative to opioids and NSAIDs in pain conditions. (Devulder, 2010) Effectively reduces the pain intensity and improves the quality of life of knee osteoarthritis patients. (Tanmoy Kanti Goswami, 2018) Shows significant improvement in pain, stiffness, and physical function in individuals with knee osteoarthritis. (Tanmoy Kanti Goswami, 2018) An attractive option for pain treatment in cancer more effectively than tramadol and pentazocine. (S Harish, 2012)

A nonsteroidal anti-inflammatory drug is used to relieve pain and inflammation. Possesses analgesic, antipyretic and anti-inflammatory properties. (Chiara Leuratti, 2019) Blocks the release of certain chemical messengers that cause pain and inflammation. Effectively treats acute moderate to severe forms of pain. (Chiara Leuratti L. L., 2019) The most effective inhibitor of the production of prostaglandin. (Alfaro) Offers rapid and sustained pain relief for patients who do not achieve pain resolution with other medications. A safe and effective medication for the treatment of rheumatic diseases. (Khan, 1987) The first choice for the treatment of acute and chronic painful and inflammatory conditions. (P A Todd, 1988) Relieves moderate to severe postoperative pain in patients undergoing dental surgery or minor orthopedic surgery. (Hannah A Blair, 2015) Considered an opioid-sparing agent for postoperative analgesia. (Ranju Singh, 2011) A suitable alternative for pain management in chronic kidney disease patients. (Sharad Sheth, 2021) As effective as indomethacin or sulindac in treating ankylosing spondylitis. (Small, 1989) Exerts substantially greater potency against cyclo-oxygenase-2 than indomethacin and naproxen. (Dr. Ajay Kumar Shukla, 2015) Provides effective and better analgesia in acute postoperative pain than tramadol. (Dr. Ajay Kumar Shukla, 2015)

Belongs to a class of anticonvulsants and antidepressants that is useful in the treatment of pain due to nerve damage. Prevents seizures and relieves pain for certain conditions in the nervous system. A beneficial pharmacological agent for numerous neurologic conditions, including neuropathic pain and epilepsy. (A Lauren Haney, 2009) Helps in relieving nerve pain and lowers the risk of seizures. Increases the number of specific nerve transmitters in the nervous system that reduces pain messages arriving in the brain. A suitable agent for the treatment of post-herpetic neuralgia. (K Chandra, 2006) More efficacious than either drug given alone for neuropathic pain. (Ian Gilron, 2009) Provides relief from neuropathic pain caused due to nerve damage and other neurological disorders.

A dual-action agent (Non-steroidal anti-inflammatory drugs, Muscle Relaxant) that eases pain, inflammation, relaxes the muscles and improves the movement of muscle. Provides a superior analgesic effect and offers effective relief from inflammation and muscle spasm. (Manish N Maladkar, 2019) Significantly reduces the intensity of pain and improves mobility in low back pain subjects. (Sanjeev Kumar, 2014) Demonstrates superiority in the reduction of pain than aceclofenac alone in patients with acute low back pain. (Aparna Mathummal Nellika, 2018) A preferred option for patients with lower backache pain accompanied by muscle spasms. (Sanjeev Kumar, 2014) More effective and without any sedation as compared to FDC of chlorzoxazone, aceclofenac and paracetamol in patients with acute lower backache associated muscle spasms. (Sanjeev Kumar, 2014) Demonstrates statistically significant decline in the pain intensity on day 3 and at the end of the treatment (day 7) in patients with acute low back pain. (Sanjeev Kumar, 2014)

An analgesic drug that relieves musculoskeletal pain in conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Possesses analgesic, anti-inflammatory, anti-edematous and antioxidant properties. (Khobre, 2017) Inhibits inflammatory manifestations in arthritis and other inflammatory diseases. (Tina Kauss, 2008) Produces certain analgesic and anti-inflammatory effects in patients with rheumatoid arthritis. (Rajendra Pavan, 2012) Offers superior analgesia as compared to Ibuprofen in surgical tooth extraction patients. (Dr Lovisha Jhunjhun Wala, 2020) Eases arthritis symptoms, including joint pain, stiffness, and improves pain after mandibular third molar surgery. (Arka Jyoti Chakraborty, 2021) A safe and effective option for the management of joint pain. Shows significant improvement in functionality in patients with osteoarthritis. An effective alternative to NSAIDs in reducing the postoperative pain associated with surgical extraction of third molars.(Dr Lovisha Jhunjhun Wala, 2020)