Zen Adsorptions Pvt. Ltd.

A Lab Cooling Type Crystallizer is an essential piece of equipment used in laboratories and pilot plants for crystallization studies and process development. It enables precise control over temperature, agitation, and cooling rate—key parameters influencing crystal formation, purity, and size distribution. The system is widely applied in the chemical, pharmaceutical, and food industries for research, scale-up, and optimization of crystallization processes.

Key Features

• Precise Temperature Control: Enables accurate management of cooling rates and setpoints for reproducible crystal growth.
  
  

• Variable Agitation Speed: Facilitates optimization of crystal size and uniformity.
  
  

• Transparent or Jacketed Vessel Options: Allows visual observation and temperature uniformity.
  
  

• Compact Design: Ideal for lab-scale trials and process development studies.
  
  

• Data Acquisition System: Records temperature, agitation, and process time for detailed analysis.
  
  

• Compatibility: Suitable for aqueous and organic solvent systems.
  
  

Applications

Pharmaceutical Industry:

• Crystallization of active pharmaceutical ingredients (APIs) and intermediates.
  
  

• Optimization of polymorphs and particle size distribution.
  
  

Chemical Industry:

• Crystallization of organic and inorganic salts.
  
  

• Recovery of valuable solutes from mother liquor.
  
  

Food and Nutraceutical Industry:

• Crystallization of sweeteners, amino acids, and nutraceutical compounds.
  
  

Research and Development:

• Fundamental studies on crystallization kinetics, solubility, and phase behavior.
  
  

Operational Parameters (Typical Range)

• Capacity: 0.5 L to 50 L (lab/pilot scale)
  
  

• Operating Temperature: -20°C to +100°C (depending on chiller and solvent system)
  
  

• Cooling Rate: 0.1°C/min to 5°C/min (programmable)
  
  

• Agitation Speed: 50 to 500 rpm
  
  

• Pressure Range: Atmospheric to full vacuum operation
  
  

• Material of Construction (MOC): Borosilicate glass, SS316, or Hastelloy based on chemical compatibility
  
  

Advantages

• Enhanced reproducibility and control over crystal properties.
  
  

• Short process time with high yield and purity.
  
  

• Applicable for both batch and continuous crystallization trials.
  
  

Valuable tool for scaling up to industrial crystallizer design.

Additional Information:

• Delivery Time: 8 Weeks

An Agitated Thin Film Evaporator (ATFE), commonly referred to as a Wiped Film Evaporator (WFE), is a highly efficient rotary evaporation system designed for the controlled evaporation, concentration, or distillation of liquids. It is especially suitable for heat-sensitive, viscous, or fouling-prone materials.

• The core structure is a jacketed shell precisely machined for optimal heat transfer.
  
  

• The high-speed rotor with blades operates with minimal clearance from the shell.
  
  

• The liquid feed enters through a feed distributor and spreads into a thin film along the heated wall.
  
  

• The rotor continuously agitates the liquid film, promoting even distribution and maximizing contact with the heated surface.
  
  

• An integrally attached entrainment separator cleans the vapors, which flow counter-current to the liquid, improving separation efficiency and vapor quality.
  
  

• The process operates in a once-through mode without recirculation, reducing product degradation and minimizing hold-up.
  
  

1. Thin Film Formation:
   
   

   • Maximizes surface area for heat transfer, ensuring uniform heating.
     
     

2. Intense Agitation:
   
   

   • Prevents fouling, scaling, and local overheating.
     
     

   • Maintains turbulent flow even for highly viscous liquids.
     
     

   • Enhances heat transfer efficiency.
     
     

3. Short Residence Time:
   
   

   • The liquid spends only a few seconds in the heated zone, minimizing thermal degradation.
     
     

4. Low Product Hold-Up:
   
   

   • Reduces material loss and improves process control.
     
     

1. Pharmaceutical Industry:
   
   

   • Vacuum distillation of bulk drugs, intermediates, and fine chemicals.
     
     

2. Chemical Industry:
   
   

   • Distillation of glycols, used lubricating oils, fatty acids, and their derivatives.
     
     

   • Processing of rubber chemicals, amines, and esters.
     
     

3. Solvent Recovery:
   
   

   • Recovery of contaminated solvents and products from residues.
     
     

• Capacity range: 0.1 sq.m to 30 sq.m surface area.
  
  

• Operating temperature: 30°C to 300°C.
  
  

• Operating pressure: From full vacuum to 2 bar (g).
  
  

• Construction materials (MOC): SS304, SS316, Hastelloy for chemical compatibility.

Additional Information:

• Delivery Time: 8 weeks

An Agitated Thin Film Evaporator (ATFE), commonly referred to as a Wiped Film Evaporator (WFE), is a highly efficient rotary evaporation system designed for the controlled evaporation, concentration, or distillation of liquids. It is especially suitable for heat-sensitive, viscous, or fouling-prone materials.

• The core structure is a jacketed shell precisely machined for optimal heat transfer.
  
  

• The high-speed rotor with blades operates with minimal clearance from the shell.
  
  

• The liquid feed enters through a feed distributor and spreads into a thin film along the heated wall.
  
  

• The rotor continuously agitates the liquid film, promoting even distribution and maximizing contact with the heated surface.
  
  

• An integrally attached entrainment separator cleans the vapors, which flow counter-current to the liquid, improving separation efficiency and vapor quality.
  
  

• The process operates in a once-through mode without recirculation, reducing product degradation and minimizing hold-up.
  
  

1. Thin Film Formation:
   
   

   • Maximizes surface area for heat transfer, ensuring uniform heating.
     
     

2. Intense Agitation:
   
   

   • Prevents fouling, scaling, and local overheating.
     
     

   • Maintains turbulent flow even for highly viscous liquids.
     
     

   • Enhances heat transfer efficiency.
     
     

3. Short Residence Time:
   
   

   • The liquid spends only a few seconds in the heated zone, minimizing thermal degradation.
     
     

4. Low Product Hold-Up:
   
   

   • Reduces material loss and improves process control.
     
     

1. Pharmaceutical Industry:
   
   

   • Vacuum distillation of bulk drugs, intermediates, and fine chemicals.
     
     

2. Chemical Industry:
   
   

   • Distillation of glycols, used lubricating oils, fatty acids, and their derivatives.
     
     

   • Processing of rubber chemicals, amines, and esters.
     
     

3. Solvent Recovery:
   
   

   • Recovery of contaminated solvents and products from residues.
     
     

• Capacity range: 0.1 sq.m to 30 sq.m surface area.
  
  

• Operating temperature: 30°C to 300°C.
  
  

• Operating pressure: From full vacuum to 2 bar (g).
  
  

• Construction materials (MOC): SS304, SS316, Hastelloy for chemical compatibility.

Additional Information:

• Delivery Time: 8 weeks

An Agitated Thin Film Evaporator (ATFE), commonly referred to as a Wiped Film Evaporator (WFE), is a highly efficient rotary evaporation system designed for the controlled evaporation, concentration, or distillation of liquids. It is especially suitable for heat-sensitive, viscous, or fouling-prone materials.

• The core structure is a jacketed shell precisely machined for optimal heat transfer.
  
  

• The high-speed rotor with blades operates with minimal clearance from the shell.
  
  

• The liquid feed enters through a feed distributor and spreads into a thin film along the heated wall.
  
  

• The rotor continuously agitates the liquid film, promoting even distribution and maximizing contact with the heated surface.
  
  

• An integrally attached entrainment separator cleans the vapors, which flow counter-current to the liquid, improving separation efficiency and vapor quality.
  
  

• The process operates in a once-through mode without recirculation, reducing product degradation and minimizing hold-up.
  
  

1. Thin Film Formation:
   
   

   • Maximizes surface area for heat transfer, ensuring uniform heating.
     
     

2. Intense Agitation:
   
   

   • Prevents fouling, scaling, and local overheating.
     
     

   • Maintains turbulent flow even for highly viscous liquids.
     
     

   • Enhances heat transfer efficiency.
     
     

3. Short Residence Time:
   
   

   • The liquid spends only a few seconds in the heated zone, minimizing thermal degradation.
     
     

4. Low Product Hold-Up:
   
   

   • Reduces material loss and improves process control.
     
     

1. Pharmaceutical Industry:
   
   

   • Vacuum distillation of bulk drugs, intermediates, and fine chemicals.
     
     

2. Chemical Industry:
   
   

   • Distillation of glycols, used lubricating oils, fatty acids, and their derivatives.
     
     

   • Processing of rubber chemicals, amines, and esters.
     
     

3. Solvent Recovery:
   
   

   • Recovery of contaminated solvents and products from residues.
     
     

• Capacity range: 0.1 sq.m to 30 sq.m surface area.
  
  

• Operating temperature: 30°C to 300°C.
  
  

• Operating pressure: From full vacuum to 2 bar (g).
  
  

• Construction materials (MOC): SS304, SS316, Hastelloy for chemical compatibility.

Additional Information:

• Delivery Time: 8 weeks

An Agitated Thin Film Evaporator (ATFE), commonly referred to as a Wiped Film Evaporator (WFE), is a highly efficient rotary evaporation system designed for the controlled evaporation, concentration, or distillation of liquids. It is especially suitable for heat-sensitive, viscous, or fouling-prone materials.

• The core structure is a jacketed shell precisely machined for optimal heat transfer.
  
  

• The high-speed rotor with blades operates with minimal clearance from the shell.
  
  

• The liquid feed enters through a feed distributor and spreads into a thin film along the heated wall.
  
  

• The rotor continuously agitates the liquid film, promoting even distribution and maximizing contact with the heated surface.
  
  

• An integrally attached entrainment separator cleans the vapors, which flow counter-current to the liquid, improving separation efficiency and vapor quality.
  
  

• The process operates in a once-through mode without recirculation, reducing product degradation and minimizing hold-up.
  
  

1. Thin Film Formation:
   
   

   • Maximizes surface area for heat transfer, ensuring uniform heating.
     
     

2. Intense Agitation:
   
   

   • Prevents fouling, scaling, and local overheating.
     
     

   • Maintains turbulent flow even for highly viscous liquids.
     
     

   • Enhances heat transfer efficiency.
     
     

3. Short Residence Time:
   
   

   • The liquid spends only a few seconds in the heated zone, minimizing thermal degradation.
     
     

4. Low Product Hold-Up:
   
   

   • Reduces material loss and improves process control.
     
     

1. Pharmaceutical Industry:
   
   

   • Vacuum distillation of bulk drugs, intermediates, and fine chemicals.
     
     

2. Chemical Industry:
   
   

   • Distillation of glycols, used lubricating oils, fatty acids, and their derivatives.
     
     

   • Processing of rubber chemicals, amines, and esters.
     
     

3. Solvent Recovery:
   
   

   • Recovery of contaminated solvents and products from residues.
     
     

• Capacity range: 0.1 sq.m to 30 sq.m surface area.
  
  

• Operating temperature: 30°C to 300°C.
  
  

• Operating pressure: From full vacuum to 2 bar (g).
  
  

• Construction materials (MOC): SS304, SS316, Hastelloy for chemical compatibility.

Additional Information:

• Delivery Time: 8 week

Our Pilot-Scale Rising Film Evaporator (RFE) is specifically designed for concentration of heat-sensitive, low-viscosity liquids under controlled conditions. This equipment is ideal for process development, R&D trials, and small-scale production in industries such as pharmaceuticals, chemicals, food & beverage, and biotechnology.

• Vertical tubular evaporator design ensures efficient heat transfer

• Rising film mechanism allows thin film formation for gentle evaporation

• Steam or hot water jacketed heat exchanger for uniform heating

• Vapor-liquid separator at the top for efficient phase separation

• Feed and product tanks with integrated flow and level controls

• Skid-mounted compact structure for easy installation and mobility

• Customizable configurations for multi-effect or solvent recovery processes

• Automation-ready with temperature, pressure, and flow control instrumentation

• Solvent recovery

• Concentration of herbal extracts and APIs

• Wastewater minimization

• Evaporation of thermally sensitive solutions

The pilot-scale RFE is engineered for scalability, making it a valuable tool for bridging the gap between lab and full-scale industrial operations. We also offer trial services, process optimization support, and custom fabrication based on client-specific requirements.

Additional Information:

• Delivery Time: 8 Weeks